Fractional Photothermolysis for Hair Follicle Induction

Part of paid clinical trials in Irvine, California.

Sponsor
University of California, Irvine
Study ID
NCT03382184
Status
Terminated

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 90 Years
Healthy Volunteers
Accepted

Interventions

  • Fraxel Dual laser — DEVICE
    The Fraxel DUAL 1550 nm laser will be used at 7 mJ, 8 pulses, 120 spots/cm2, treatment level 3 (9% coverage) for hair regrowth.
  • Halo laser — DEVICE
    The Halo hybrid laser will be used per protocol due to its dynamic thermal optimization technology for hair regrowth.

Study Details

This study is being done to evaluate the effects of fractional photothermolysis (known as laser resurfacing) using fractional laser for the induction of hair follicles via skin rejuvenation in subjects with scalp alopecia (specifically, alopecia on the superior forehead at the frontal hairline). Fractional photothermolysis has been shown to be effective in promoting hair growth. The investigators will study 50 subjects who will be treated 6-10 times at 2-4 week intervals. Each participant will have half of their head treated with a laser, either Fraxel DUAL 1550 or Halo by Sciton, and the other half of their head will be left untreated as a control. Half of the individuals will randomly be assigned to the group to be treated with Fraxel DUAL 1550, and the other half will be treated with Halo by Sciton. Visual observation and digital, photographic, non-invasive imaging will be used to compare the treated and untreated area to assess for differences in hair follicle stimulation rates, number and density of hairs. As noted above, the types of lasers we plan to use include the non-ablative fractional laser settings for the Fraxel DUAL 1550 and Halo by Sciton. A fractional laser is a laser that directs an intense burst of laser energy on the skin. The treatment deposits heat deep into the dermis to tighten skin and stimulate collagen remodeling. The necrotic (death of cells or tissue) injury heals rapidly and adverse effects are few. Laser resurfacing is commonly used for rejuvenation of the skin to improve quality, tone, and texture.

Key Dates

Start date
Oct 20, 2017
Status verified
Mar 2026
Primary completion
May 29, 2019
Completion
May 29, 2019

Study Design

Enrollment
5 participants (actual)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Fraxel DUAL 1550 nm
    The Fraxel DUAL 1550 nm laser will be used at 7 mJ, 8 pulses, 120 spots/cm2, treatment level 3 (9% coverage) for hair regrowth. 25 patients with alopecia will be part of this group.
  • Experimental: Halo Hybrid Laser 1550 nm
    The Halo laser will be used per protocol due to the dynamic thermal optimization technology for hair regrowth. 25 patients with alopecia will be part of this group.

Primary Outcome Measure

Hair Density Change by as Seen by Dermoscopy [ Time Frame: 24 weeks ]

Locations (1)

FacilityCityStateZIPSite coordinators
University of California, Irvine, Department of Dermatology, Dermatology Clinical Research Center, Hewitt HallIrvineCalifornia92697-

Find similar trials in Irvine, CA

By research site
University of California, Irvine, Department of Dermatology, Dermatology Clinical Research Center, Hewitt Hall· Irvine, CA

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