Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery

Part of paid clinical trials in St. George, Utah.

Sponsor
Jason Ahee, M.D.
Study ID
NCT03244072
Phase
PHASE2/PHASE3
Status
Not Yet Recruiting

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Conditions

  • Endophthalmitis

Eligibility Criteria

Sex
ALL
Age
40 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Moxifloxacin — DRUG
    Intracameral injection
  • Placebo — DRUG
    intracameral injection

Study Details

Intracameral injection of 0.1% moxifloxacin solution after cataract surgery to prevent endophthalmitis

Key Dates

Start date
Jun 1, 2026
Status verified
Aug 2025
Primary completion
Oct 31, 2030
Completion
Oct 31, 2031

Study Design

Enrollment
60,000 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Active Comparator: Treatment group
    Intracameral injection of moxifloxacin solution after cataract surgery
  • Placebo Comparator: Placebo group
    Intracameral injection of placebo after cataract surgery

Primary Outcome Measure

Endophthalmitis after cataract surgery [ Time Frame: Subjects will undergo eye examinations at one day, one week, and one month post-operatively ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Zion Eye InstituteSt. GeorgeUtah84790
Jason Ahee, M.D.

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