Modulating Movement Intention Via Cortical Stimulation

Part of paid clinical trials in New York, New York.

Sponsor
NYU Langone Health
Study ID
NCT03233399
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Accepted

Interventions

  • Sham TMS3 stimulation — DEVICE
    half of the subjects will receive sham stimulation first
  • rTMS of left or right angular gyrus (AG) or frontal cortex (FC) — DEVICE
    Half of the subjects will receive active stimulation first; A subject may receive either TMS or tDCS stimulation, but not both, over the course of the sub-study.
  • Anodal tDCS of left or right AG or FC — DEVICE
    Half of the subjects will receive active stimulation first; A subject may receive either TMS or tDCS stimulation, but not both, over the course of the sub-study.

Study Details

The purpose of this protocol is to learn about movement intention and volition. To improve such knowledge, investigators will conduct sub-studies using multiple non-invasive methodologies. These results could provide preliminary data for subsequent studies evaluating local and global efficacy of plasticity-inducing treatments for PMD symptoms.

Key Dates

Start date
Jul 20, 2017
Status verified
Nov 2025
Primary completion
May 31, 2027
Completion
May 31, 2027

Study Design

Enrollment
30 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Active Comparator: Healthy Patients
    All healthy volunteers will complete the healthy volunteer form, MRI safety screening form, and the Montreal Cognitive Assessment (MOCA).
  • Active Comparator: PMD/PNES patients
    PMD and PNES subjects will be referred by the treating

Primary Outcome Measure

Changes in signal intensity measured using of tDCS [ Time Frame: 30 Minutes ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
New York University School of MedicineNew YorkNew York10016
Steven Stork
[email protected]
212-263-0001
Biyu He, MD (PRINCIPAL_INVESTIGATOR)

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