Neurocognitive Functioning With Genu-Sparing Whole Brain Radiation Therapy for Brain Metastases

Part of paid clinical trials in Washington D.C., District of Columbia.

Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Study ID
NCT03223922
Status
Recruiting
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Conditions

  • Brain Metastases

Eligibility Criteria

Sex
ALL
Age
18 Years - 100 Years
Healthy Volunteers
Not accepted

Interventions

  • whole brain radiation therapy — RADIATION
    Corpus Callosum Genu-Sparing Whole Brain Radiation Therapy Genu-sparing whole brain radiation therapy (GS-WBRT) 30 Gy in 3 Gy per fraction

Study Details

This is a trial that evaluates the preservation of cognition and neuropsychiatric function following genu-sparing whole brain radiation in patients with brain metastases.

Key Dates

Start date
Jul 19, 2017
Status verified
Jun 2025
Primary completion
Dec 31, 2026
Completion
Dec 31, 2030

Study Design

Enrollment
24 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Corpus Callosum Genu-Sparing Whole Brain Radiation Therapy
    Genu-sparing whole brain radiation therapy (GS-WBRT) 30 Gy in 3 Gy per fraction

Primary Outcome Measure

Rate of change of cognitive function [ Time Frame: 4 months ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
Sibley Memorial HospitalWashington D.C.District of Columbia20016
Victoria Croog, MD
[email protected]
202-537-4787
The SKCCC at Johns HopkinsBaltimoreMaryland21287
Kristin Redmond, MD
[email protected]
410-614-1642
Tracy Vannorsdall, PhD (SUB_INVESTIGATOR)
Haris Sair, MD (SUB_INVESTIGATOR)
Russell Hales, MD (SUB_INVESTIGATOR)
Lawrence Kleinberg, MD (SUB_INVESTIGATOR)
Brandi Page, MD (SUB_INVESTIGATOR)
Deborah Frassica, MD (SUB_INVESTIGATOR)
Fariba Asrari, MD (SUB_INVESTIGATOR)

Find similar trials in Washington D.C., DC

By research site
Sibley Memorial Hospital· Washington D.C., DCThe SKCCC at Johns Hopkins· Baltimore, MD

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