Multi-Parametric MRI for Renal Transplantation

Part of paid clinical trials in Minneapolis, Minnesota.

Sponsor
University of Minnesota
Study ID
NCT03192007
Status
Not Yet Recruiting

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Conditions

  • Renal Transplant Rejection

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Magnetic Resonance Imaging — DEVICE
    Investigate anatomic and functional characteristics of transplant kidneys using MRI

Study Details

The goals of this study are: * To optimize and evaluate multiple kidney MRI methods; and * To investigate the potential of MRI in the assessment of transplant kidney functions; To achieve these goals, we will perform pilot MRI studies with kidney transplant patients. We will study if MRI can reflect different levels of kidney function. The investigators will also evaluate if MRI can differentiate causes for declining kidney function. Finally, the investigators will explore how MRI measures changes before and after medical treatment for worsening kidney function. You may be invited for MRI exams with different exam options. An MRI exam may use either of two types of MRI machines at the center for magnetic resonance research (CMRR): the 3 Tesla (3T) scanner and the 7 Tesla (7T) scanner. You may also be invited for a multi-session exam. A description of the MRI exam types with different exam options and the types of multi-session exams is provided later in this document.

Key Dates

Start date
Jul 1, 2027
Status verified
Sep 2025
Primary completion
Dec 31, 2028
Completion
Dec 31, 2028

Study Design

Enrollment
140 participants (estimated)

Arms

  • Arm: Patients with Stable Renal Function
    Patients will be given MRI
  • Arm: Patients with Worsening Renal Function due to complications
    MRI

Primary Outcome Measure

Anatomic and functional MRI characteristics in transplant kidneys with stable renal function [ Time Frame: Baseline ]

Locations (1)

FacilityCityStateZIPSite coordinators
CMMRMinneapolisMinnesota55455-

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By research site
CMMR· Minneapolis, MN

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