Phase 2 Trial of Apatinib Mesylate in Locally Advanced/Metastatic Differentiated Thyroid Carcinoma
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
- Study ID
- NCT03167385
- Phase
- PHASE2
- Status
- Unknown
Conditions
- Differentiated Thyroid Carcinoma
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 75 Years
- Healthy Volunteers
- Not accepted
Interventions
- Apatinib Mesylate — DRUGoral intake of Apatinib Mesylate 500mg once a day until progression of diesase or severe adverse effect
Study Details
This is a non-randomized, phase II, open label study of Apatinib Mesylate in patients with with locally advanced or metastatic differentiated thyroid carcinoma (DTC). The purpose of this study is to evaluate the efficacy and safety of apatinib in patients with locally advanced or metastatic differentiated thyroid carcinoma.
Key Dates
- Start date
- Mar 22, 2017
- Status verified
- Mar 2017
- Primary completion
- Jan 31, 2019
- Completion
- Dec 31, 2020
Study Design
- Enrollment
- 20 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: ExperitmentalContinuous oral intake of Apatinib Mesylate (500mg), once a day, until progression of disease or severe adverse effect.
Primary Outcome Measure
disease control rate [ Time Frame: within two weeks of drug administration ]
Central Contacts
- Ming Gao, MD862223340123
- Xiangqian Zheng, MD862223340123