Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions

Part of paid clinical trials in San Antonio, Texas.

Sponsor
The University of Texas Health Science Center at San Antonio
Study ID
NCT03160274
Status
Recruiting
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Conditions

  • Associated Conditions
  • Bone Cancer
  • Inherited Cancer Syndrome
  • Kidney Neoplasms
  • Other Cancer
  • Paraganglioma
  • Pheochromocytoma
  • Thyroid Neoplasms

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Accepted

Interventions

  • Genetic screening — GENETIC
    Germline and/or tumor samples will be screened for mutations

Study Details

Pheochromocytomas and paragangliomas are neural crest-derived tumors of the nervous system that are often inherited and genetically heterogeneous. Genetic screening is recommended for patients and their relatives, and can guide clinical decisions. However, a mutation is not found in all cases. The aims of this proposal are to: 1) to map gene(s) involved in pheochromocytoma, and 2) identify genotype-phenotype correlations in patients with pheochromocytoma/paraganglioma of various genetic origins.

Key Dates

Start date
Oct 19, 2005
Status verified
Oct 2025
Primary completion
Dec 31, 2030
Completion
Dec 31, 2030

Study Design

Enrollment
2,000 participants (estimated)

Primary Outcome Measure

Identification of germline driver mutation [ Time Frame: through study completion- average time approximately 6 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Texas Health Science CenterSan AntonioTexas78229
Patricia L Dahia
[email protected]
210-567-4866

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By research site
University of Texas Health Science Center· San Antonio, TX

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