Nivolumab in Recurrent or Metastatic Salivary Gland Carcinoma of the Head and Neck
- Sponsor
- UNICANCER
- Study ID
- NCT03132038
- Phase
- PHASE2
- Status
- Completed
Conditions
- Metastatic Cancer
- Recurrent Cancer
- Salivary Gland Carcinoma
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Nivolumab — DRUG3 mg/kg, every two weeks, during a maximum of one year
Study Details
INDICATION: Patients with recurrent and/or metastatic salivary glands carcinoma who have progressed during the 6 months period before entering the study and who are eligible for nivolumab monotherapy.
Key Dates
- Start date
- Mar 24, 2017
- Status verified
- Jan 2022
- Primary completion
- Jan 1, 2019
- Completion
- Oct 20, 2021
Study Design
- Enrollment
- 98 participants (actual)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: NivolumabNivolumab will be given every two weeks for a maximum of one year (12 cycles) at a dose of 3 mg/kg to be administered as a 60 minute IV infusion
Primary Outcome Measure
non-progression rate [ Time Frame: 6 months ]
Related Studies
- Harvesting Cells for Experimental Cancer TreatmentsEnrolling By Invitation · National Cancer Institute (NCI) · Bethesda, Maryland
- ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid TumorsPHASE1/PHASE2 · Recruiting · Immatics US, Inc. · Stanford, California
- Androgen Deprivation Therapy (ADT) and Pembrolizumab for Advanced Stage Androgen Receptor-positive Salivary Gland CarcinomaPHASE2 · Recruiting · Manish Patel · Chicago, Illinois
- Role of Ablative Radiotherapy in the Management of Metastatic Disease: A Patient Data RegistryRecruiting · Duke University · Cary, North Carolina