Interventions for Postoperative Delirium: Biomarker-3

Part of paid clinical trials in Madison, Wisconsin.

Sponsor
University of Wisconsin, Madison
Study ID
NCT03124303
Status
Recruiting
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Conditions

  • Delirium

Eligibility Criteria

Sex
ALL
Age
60 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • High Density-Electroencephalogram — PROCEDURE
    EEG is a safe non-invasive technology without complications that may be used to help diagnose delirium
  • Magnetic Resonance Imaging — PROCEDURE
    MRI scan of brain
  • Blood specimen collection — PROCEDURE
    Blood will be collected from participants
  • Pupillometry — DIAGNOSTIC_TEST
    A pupillometer is a device that measures the size of the pupils.

Study Details

The IPOD-B3 study aims to characterize the relationship between premorbid brain activity and postoperative delirium in patients undergoing major surgery. This is a expansion of the NeuroVISION Bolt-On study, NCT01980511.

Key Dates

Start date
Feb 13, 2017
Status verified
Dec 2025
Primary completion
Dec 31, 2029
Completion
Dec 31, 2029

Study Design

Enrollment
468 participants (estimated)

Arms

  • Arm: Participants 1-320
    First 320 participants enrolled
  • Arm: Participants 321-470
    Final 150 participants enrolled

Primary Outcome Measure

Functional Connectivity [ Time Frame: Pre-operative measure: Up to 4 weeks prior to surgery. Post-operative measure: Post-Operative days 1-4 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Wisconsin-MadisonMadisonWisconsin53792
David Kunkel, BS
[email protected]
608-262-6469
Frankie Ingram, BS
[email protected]
608-262-6469
Robert Pearce, MD PhD (PRINCIPAL_INVESTIGATOR)

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By research site
University of Wisconsin-Madison· Madison, WI

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