Mesylate Apatinib for Stage Ⅳ STS After Failure of Chemotherapy
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
- Study ID
- NCT03121846
- Phase
- PHASE2
- Status
- Unknown
Conditions
- Soft Tissue Sarcoma, Adult, Stage II
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 70 Years
- Healthy Volunteers
- Not accepted
Interventions
- Apatinib — DRUGApatinib 500 mg is administered orally daily, until disease progression or untolerable toxicity.
Study Details
This is a Prospective, Open-label, Single-Arm, Multi-center phase II clinical trial evaluating the efficacy and safety of Apatinib for Chemotherapy Failure Ⅳ Stage Soft Tissue Sarcoma.
Key Dates
- Start date
- May 1, 2017
- Status verified
- Mar 2017
- Primary completion
- Nov 1, 2018
- Completion
- May 1, 2019
Study Design
- Enrollment
- 80 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: apatinib groupapatinib 500mg po qd, 28 days for a cycle.
Primary Outcome Measure
Progression-free survival (PFS) [ Time Frame: 2 year ]
Central Contacts
- Jilong Yang, M.D., Ph.D.+8618622221626