A Study to Test the Safety and Effectiveness of Nivolumab Combined With Daratumumab in Patients With Pancreatic, Non-Small Cell Lung or Triple Negative Breast Cancers, That Have Advanced or Have Spread

Part of paid clinical trials in Long Beach, California.

Sponsor
Bristol-Myers Squibb
Study ID
NCT03098550
Phase
PHASE1/PHASE2
Status
Completed

Conditions

  • Advanced Cancer

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Nivolumab — BIOLOGICAL
    Specified dose on specified days
  • Daratumumab — BIOLOGICAL
    Specified dose on specified days

Study Details

The purpose of this study is to determine whether a combination of Nivolumab and Daratumumab is safe and effective when treating Pancreatic, Non-Small Cell Lung or Triple Negative Breast Cancers, that have advanced or have spread.

Key Dates

Start date
Jun 15, 2017
Status verified
Jul 2021
Primary completion
Jul 6, 2020
Completion
Jul 6, 2020

Study Design

Enrollment
105 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Immunotherapy Combination
    TNBC and PAC participants who are deriving clinical benefit will continue to be treated with the nivolumab plus daratumumab combination therapy
  • Experimental: Nivolumab Monotherapy
    NSCLC patients who are deriving clinical benefit will be treated with nivolumab monotherapy

Primary Outcome Measure

Number of Participants With Adverse Events (AEs) [ Time Frame: From first dose to 30 days post last dose (up to 34 months) ]

Locations (5)

FacilityCityStateZIPSite coordinators
Pacific Shores Medical GroupLong BeachCalifornia90813-
University Of ColoradoAuroraColorado80045-
Moffitt Cancer CenterTampaFlorida33612-
University Of MichiganAnn ArborMichigan48109-
Providence Portland Medical CenterPortlandOregon97213-

Find similar trials in Long Beach, CA

By research site
Pacific Shores Medical Group· Long Beach, CAUniversity Of Colorado· Aurora, COMoffitt Cancer Center· Tampa, FLUniversity Of Michigan· Ann Arbor, MIProvidence Portland Medical Center· Portland, OR

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