Apatinib Mesylate Combined With Pemetrexed in the Treatment of Pretreated Advanced Non-squamous Non-small Cell Lung Cancer
- Sponsor
- Wuling Ou
- Study ID
- NCT02974933
- Phase
- PHASE2
- Status
- Unknown
Conditions
- Nonsmall Cell Lung Cancer
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 70 Years
- Healthy Volunteers
- Not accepted
Interventions
- Apatinib combined with pemetrexed — DRUGFor those pretreated non-squamous non-small cell lung cancer, treat with apatinib 500mg Qd, po.combined with pemetrexed continue until disease progression
Study Details
The purpose of this study is to evaluate the efficacy of apatinib mesylate combined with pemetrexed alone in advanced non-small cell lung cancer patients in the second or second line of treatment of progression-free survival
Key Dates
- Start date
- Nov 30, 2016
- Status verified
- Feb 2017
- Primary completion
- Nov 30, 2017
- Completion
- Nov 30, 2018
Study Design
- Enrollment
- 48 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: apatinibcombined with pemetrexed
Primary Outcome Measure
progression free survival [ Time Frame: 4 weeks ]
Central Contacts
- Ou Wu Ling, MD
Related Studies
- Pilot Study of Performance Status 2 vs. Performance Status 0-1 Non-small Cell Lung Cancer Patients Treated With Chemo/ImmunotherapyPHASE2 · Recruiting · Wake Forest University Health Sciences · Winston-Salem, North Carolina
- Patient-centered, Optimal Integration of Survivorship and Palliative CareRecruiting · Massachusetts General Hospital · Boston, Massachusetts
- Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing TumorsPHASE1 · Recruiting · Orano Med Theranostics, SAS · Chicago, Illinois
- A Phase 1 and 2 Study of VMD-102 in Hepatocellular Carcinoma and Other Solid TumorsPHASE1/PHASE2 · Not Yet Recruiting · VM Discovery, Inc. · Scottsdale, Arizona