Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors

Conditions

• Brain Neoplasm
• Metastatic Malignant Neoplasm in the Brain
• Recurrent Brain Neoplasm

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• Direct Electrocortical Stimulation — PROCEDURE
  Undergo direct electrocortical stimulation
• Electrocorticography — OTHER
  Undergo electrocorticography

Study Details

This pilot clinical trial studies how well electrocorticography works in mapping functional brain areas during surgery in patients with brain tumors. Using a larger than the standard mapping grid currently used during brain tumor surgery or a high-definition grid for electrocorticogram brain mapping may help doctors to better identify which areas of the brain are active during specific limb movement and speech during surgery in patients with brain tumors.

Key Dates

Start date

Jul 22, 2016

Status verified

May 2026

Primary completion

Jan 1, 2027

Completion

Jan 1, 2028

Study Design

Enrollment

75 participants (estimated)

Allocation

NA

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Arms

• Experimental: Diagnostic (electrocorticography)
  Patients undergo tumor resection. During surgery, patients also undergo electrocorticography with either the CorTec high resolution hybrid grid, the PMT high-resolution grid, or the Ad-Tech grid followed by direct electrocortical stimulation.

Primary Outcome Measure

Electrocorticogram (ECoG) [ Time Frame: Up to 6 months (± 4 weeks) ]

Central Contacts

• Sujit Prabhu, MD
  713-792-2400
  [email protected]

Locations (1)

Find similar trials in Houston, TX

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