Cortical Plasticity in Spastic Diplegia After Selective Dorsal Rhizotomy

Part of paid clinical trials in Houston, Texas.

Sponsor
The University of Texas Health Science Center, Houston
Study ID
NCT02535936
Status
Recruiting
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Conditions

  • Spastic Diplegia

Eligibility Criteria

Sex
ALL
Age
3 Years - 18 Years
Healthy Volunteers
Not accepted

Interventions

  • 3Tesla MRI with DTI-MRI and rsfcMRI under general anesthesia — PROCEDURE
    2 post-operative MRI's at 2 months and 12 months

Study Details

The purpose of this study is to characterize the cortical connectivity changes in the brain of spastic diplegic children after Selective Dorsal Rhizotomy.

Key Dates

Start date
Aug 31, 2015
Status verified
Dec 2024
Primary completion
Jan 1, 2030
Completion
Jan 1, 2031

Study Design

Enrollment
15 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC

Arms

  • Other: 3Tesla MRI with DTI-MRI and rsfcMRI
    Patients will receive 2 post-operative MRI's with DTI and rsfcMRI at 2 months and 12 months.

Primary Outcome Measure

Change in Fractional Anisotropy as assessed by brain MRI with diffusion tractography imaging (DTI) sequences [ Time Frame: Baseline and 12 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UTHealth & Children's Memorial Hermann HospitalHoustonTexas77030
Manish N Shah, MD
[email protected]
713-500-7410
Bangning L Yu, RN
[email protected]
713 500-7363

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By research site
UTHealth & Children's Memorial Hermann Hospital· Houston, TX

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