Imaging Acquisition and Analysis Methods for Optimization of MRI Radiation Oncology Simulation and Response Assessment

Part of paid clinical trials in Basking Ridge, New Jersey.

Sponsor
Memorial Sloan Kettering Cancer Center
Study ID
NCT02422550
Status
Recruiting
Apply to this trial

Conditions

  • Radiation Therapy

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • MRI or CT — DEVICE
    Participants enrolled on this protocol may undergo multiple MRI or CT examinations periodically over the course of their treatment and follow-up if they are participating in a development project related to tumor response assessment. Volunteers enrolled on this protocol may undergo multiple MRI examinations periodically for studies of reproducibility.

Study Details

Magnetic resonance imaging (MRI) is currently one of the standard diagnostic imaging methods used to diagnose tumor stage before treatment in the Radiation Oncology Department. It is also used to check responses to radiation after treatment. However, MRI isn't traditionally used in planning for radiation treatment or in checking treated tumor and tissue changes during radiation treatment. The goal is to find out the possible benefits of MRI imaging techniques in these settings of radiation treatment. The research aims are to study the possibility of using devices with new abilities such as the MR-Linac. The MR-Linac combines a radiation treatment machine with a diagnostic MRI scanner. This device will improve the quality of MRI-guided radiation treatment. The MR-Linac has functions that are currently not available in other combined imaging and radiation delivery devices. The MR-Linac does not provide additional imaging capabilities that are not currently available in other imaging devices. Participating in this study would NOT change the current treatment plans, this will allow the investigators to use the MRI methods in research and future patient care.

Key Dates

Start date
Apr 9, 2015
Status verified
Mar 2026
Primary completion
Apr 30, 2027
Completion
Apr 30, 2027

Study Design

Enrollment
837 participants (estimated)

Arms

  • Arm: participants undergoing radiation therapy & normal volunteers
    Protocol participation will consist of one or more research MRI or CT exams not to exceed 45 minutes.

Primary Outcome Measure

evaluate the feasibility of new MRI or CT applications [ Time Frame: 5 years ]

Central Contacts

  • Nancy Lee, MD
    212-639-3341
  • Simon Powell, MD
    212-639-6072

Locations (7)

FacilityCityStateZIPSite coordinators
Memorial Sloan Kettering Basking Ridge (Consent only)Basking RidgeNew Jersey07920
Nancy Lee, MD
212-639-3341
Memorial Sloan Kettering Monmouth (Consent only)MiddletownNew Jersey07748
Nancy Lee, MD
212-639-3341
Memorial Sloan Kettering Bergen (Consent only )MontvaleNew Jersey07645
Nancy Lee, MD
212-639-3341
Memorial Sloan Kettering Commack (Consent Only)CommackNew York11725
Nancy Lee, MD
212-639-3341
Memorial Sloan Kettering Westchester (Consent only)HarrisonNew York10604
Nancy Lee, MD
212-639-3341
Memorial Sloan Kettering Cancer CenterNew YorkNew York10065
Nancy Lee, MD
212-639-3341
Simon Powell, MD
212-639-6072
Nancy Lee, MD (PRINCIPAL_INVESTIGATOR)
Memorial Sloan Kettering Nassau (Consent only)UniondaleNew York11553
Nancy Lee, MD
212-639-3341

Find similar trials in Basking Ridge, NJ

By research site
Memorial Sloan Kettering Basking Ridge (Consent only)· Basking Ridge, NJMemorial Sloan Kettering Monmouth (Consent only)· Middletown, NJMemorial Sloan Kettering Bergen (Consent only )· Montvale, NJMemorial Sloan Kettering Commack (Consent Only)· Commack, NYMemorial Sloan Kettering Westchester (Consent only)· Harrison, NYMemorial Sloan Kettering Cancer Center· New York, NY

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