Split-Face Prospective Study Comparing Botox to Xeomin for the Treatment of Facial Wrinkles

Conditions

• Facial Wrinkles

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Accepted

Interventions

• Xeomin to right side of face in half of the subjects; Xeomin to left side of face in the other half of subjects — DRUG
  Subjects were randomized to which side of the face would be treated with Xeomin.
• Botox to right side of face in half of the subjects (randomized); Botox to the left side of the face in the other half of subjects — DRUG
  Subjects were randomized to which side of the upper face would be treated with Botox

Study Details

The aim of this prospective, randomized, double-blind, intraindividual split face study will be to compare onabotulinumtoxinA to incobotulinumtoxinA for the correction of facial wrinkles using a 1:1 dose ratio.

Key Dates

Start date

Jul 31, 2012

Status verified

Apr 2014

Primary completion

Nov 30, 2012

Completion

Nov 30, 2013

Study Design

Enrollment

45 participants (actual)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Arms

• Active Comparator: Xeomin right side; Xeomin to left side of face
  Patients were randomized as to which side of the face was treated with Xeomin.
• Active Comparator: Botox right side; Botox to left side
  Patients were randomized as to which side of the face was treated with Botox.

Primary Outcome Measure

Change in Wrinkles Score [ Time Frame: Preinjection assessment; assessment at 3 days, 2 weeks, 3 months, 4 months post-injection ]

Locations (1)

Find similar trials in Sarasota, FL