Kidney Cancer DNA Registry

Conditions

• Renal Cancer

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Accepted

Interventions

• salvia for germline DNA — OTHER
• the Kidney Cancer Questionnaire — BEHAVIORAL
  Patients will complete the appropriate surveys on either paper or on the computer/iPad in the office using REDCap software. If patients are unable to complete their questionnaires at the time of their in-office visit, a link to the questionnaires in REDCap will be emailed to them. The survey data that is collected in REDCap will be stored in REDCap. Clinic staff may also call patients to remind patients to complete questionnaires.
• Family History Questionnaire (when applicable) — BEHAVIORAL
  Patients will complete the appropriate surveys on either paper or on the computer/iPad in the office using REDCap software. If patients are unable to complete their questionnaires at the time of their in-office visit, a link to the questionnaires in REDCap will be emailed to them. The survey data that is collected in REDCap will be stored in REDCap. Clinic staff may also call patients to remind patients to complete questionnaires.
• Blood draw — OTHER
• Epidemiologic Questionnaire — BEHAVIORAL
  Patients will complete the appropriate surveys on either paper or on the computer/iPad in the office using REDCap software. If patients are unable to complete their questionnaires at the time of their in-office visit, a link to the questionnaires in REDCap will be emailed to them. The survey data that is collected in REDCap will be stored in REDCap. Clinic staff may also call patients to remind patients to complete questionnaires.

Study Details

This registry will help us develop better methods of: * Preventing these cancers * Diagnosing these cancers * Treating these cancers

Key Dates

Start date

Mar 31, 2014

Status verified

Apr 2026

Primary completion

Mar 31, 2027

Completion

Mar 31, 2027

Study Design

Enrollment

750 participants (estimated)

Arms

• Arm: kidney cancer patients receiving care at MSKCC
  Participation will consist of completing the Kidney Cancer Questionnaire Family History Questionnaire and complete the Epidemiologic Questionnaire (when applicable,), and providing a blood sample and saliva sample for germline DNA. In cases where tissue samples from surgically derived tumor specimens are obtained these will used to determine genetic alterations related to cancer predisposition or pathogenicity.
• Arm: relatives of patients with kidney cancer
  Participation will consist of completing the Kidney Cancer Questionnaire Family History Questionnaire (when applicable,), and providing a saliva sample for germline DNA. In cases where tissue samples from surgically derived tumor specimens are obtained these will used to determine genetic alterations related to cancer predisposition or pathogenicity.
• Arm: healthy controls who are unrelated & do not have hx of cancer
  Participation will consist of completing the Kidney Cancer Questionnaire Family History Questionnaire (when applicable,), and providing a saliva sample for germline DNA. In cases where tissue samples from surgically derived tumor specimens are obtained these will used to determine genetic alterations related to cancer predisposition or pathogenicity.
• Arm: high risk
  Participation will consist of completing the Epidemiologic Questionnaire, Family History Questionnaire (if + FH), provide saliva and blood sample , referral for screening evaluation

Primary Outcome Measure

establish a kidney cancer registry [ Time Frame: 5 years ]

Central Contacts

• Jonathan Coleman, MD
  646-422-4432
• Kenneth Offit, MD
  646-888-4050

Locations (7)

Find similar trials in Basking Ridge, NJ

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