A Clinical Study in Three-arm of Lurbinectedin (PM01183) Alone or in Combination With Gemcitabine and a Control Arm With Docetaxel as Second Line Treatment in Non-Small Cell Lung Cancer (NSCLC) Patients
Part of paid clinical trials in New York, New York.
- Sponsor
- PharmaMar
- Study ID
- NCT01951157
- Phase
- PHASE2
- Status
- Completed
Conditions
- Non-Small Cell Lung Cancer (NSCLC)
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 75 Years
- Healthy Volunteers
- Not accepted
Interventions
- Docetaxel — DRUGPowder for solution for infusion
- Gemcitabine — DRUGPowder for solution for infusion
- Lurbinectedin (PM01183) — DRUGPowder for concentrate for solution for infusion
Study Details
A clinical study of lurbinectedin(PM01183) alone or in combination with gemcitabine in comparison to docetaxel for the treatment of unresectable non-small cell lung cancer (NSCLC)patients
Key Dates
- Start date
- Sep 11, 2013
- Status verified
- Sep 2019
- Primary completion
- Nov 30, 2016
- Completion
- Nov 30, 2016
Study Design
- Enrollment
- 69 participants (actual)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Active Comparator: A - docetaxel75 mg/m2 docetaxel day 1, 1-hour intravenous, every three weeks
- Experimental: B - lurbinectedin (PM01183)3.2 mg/m2 PM01183, day 1, 1-hour intravenous, every three weeks
- Experimental: C - gemcitabine + lurbinectedin (PM01183)800 mg/m2 gemcitabine / 1.6 mg/m2 PM01183 both on day 1 and day 8, 30-minutes gemcitabine/1-hour PM01183 intravenous, every three weeks
Primary Outcome Measure
Progression-free Survival Rate at Four Months (PFS4) [ Time Frame: At month four after patient inclusion ]
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| - | New York | New York | - | - |
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