Bendamustine, Gemcitabine and Vinorelbine (BeGEV) as Induction Therapy in Relapsed/Refractory Hodgkin's Lymphoma Patients
- Sponsor
- Armando Santoro, MD
- Study ID
- NCT01884441
- Phase
- PHASE2
- Status
- Unknown
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Bendamustine — DRUGSchedule: Day 2: Bendamustine 90mg/mq Day 3: Bendamustine 90mg/mq for a maximum of 4 cycles
- Gemcitabine — DRUGDay 1: Gemcitabine 800mg/mq, Day 4: Gemcitabine 800mg/mq for a maximum of 4 cycles
- Vinorelbine — DRUGDay 1 Vinorelbine 20mg/mq for a maximum of 4 cycles
Study Details
Test of bendamustine in combination with gemcitabine and vinorelbine could contribute to a higher response rate with the reduction of toxic side effects
Key Dates
- Start date
- Jul 31, 2011
- Status verified
- Jan 2014
- Primary completion
- Jul 31, 2014
- Completion
- Jul 31, 2016
Study Design
- Enrollment
- 59 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: BeGEVBendamustine, Gemcitabine and Vinorelbine (BeGEV)
Primary Outcome Measure
Response Rate [ Time Frame: 3 months ]
Central Contacts
- Armando Santoro, MD+39 (0)2 8224
- Rita Mazza, MD+39 (0)2 8224
Related Studies
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- CD30 CAR T Cells, Relapsed CD30 Expressing Lymphoma (RELY-30)PHASE1 · Recruiting · Baylor College of Medicine · Houston, Texas
- A Phase II Study of the Combination of Azacitidine and Pembrolizumab for Patients Relapsed/Refractory Hodgkin's LymphomaPHASE2 · Recruiting · M.D. Anderson Cancer Center · Houston, Texas