Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program

Part of paid clinical trials in Houston, Texas.

Sponsor
M.D. Anderson Cancer Center
Study ID
NCT01772771
Status
Recruiting
Apply to this trial

Conditions

  • Glioma
  • Hematopoietic and Lymphoid Cell Neoplasm
  • Malignant Solid Neoplasm
  • Melanoma
  • Sarcoma

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Interventions

  • Biospecimen Collection — PROCEDURE
    Undergo collection of blood, saliva/buccal swab samples
  • Genetic Testing — OTHER
    Correlative studies
  • Medical Chart Review — OTHER
    Review of medical records

Study Details

This study performs standardized testing of tumor tissue samples to learn which genes are mutated (have changed) in order to provide personalized cancer therapy options to cancer patients at MD Anderson. This may help doctors use testing information on tumors to identify clinical trials that may be most relevant to patients. Researchers may also use the information learned from this study to develop a database of the different kinds of mutations in cancer-related genes.

Key Dates

Start date
Mar 1, 2012
Status verified
Feb 2026
Primary completion
Mar 1, 2032
Completion
Mar 1, 2033

Study Design

Enrollment
12,000 participants (estimated)

Arms

  • Arm: Ancillary-correlative (biospecimen collection, chart review)
    Patients' previously collected tissue samples are analyzed. Patients may also undergo collection of blood, saliva or buccal samples for analysis. Patients' medical records are reviewed.

Primary Outcome Measure

Frequency of mutations and co-mutations [ Time Frame: 20 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
M D Anderson Cancer CenterHoustonTexas77030
Funda Meric-Bernstam
713-792-6940
Funda Meric-Bernstam (PRINCIPAL_INVESTIGATOR)

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M D Anderson Cancer Center· Houston, TX

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