Phase IV Study On Muscle Activity Of Two Commercial Preparations Of Botulinum

Sponsor
Hexsel Dermatology Clinic
Study ID
NCT01728337
Phase
PHASE4
Status
Completed

Conditions

  • Sun-induced Wrinkles

Eligibility Criteria

Sex
FEMALE
Age
18 Years - 60 Years
Healthy Volunteers
Accepted

Interventions

  • Dysport — DRUG
    Dysport® was injected on the right side of the forehead and Xeomin® was injected on the left side of the forehead.
  • Xeomin — DRUG
    Xeomin® was injected on the right side of the forehead and Dysport® was injected on the left side of the forehead

Study Details

this study was proposed to provide more scientific and objective data on the clinical and aesthetic effects of these two toxins (Dysport and Xeomin).

Key Dates

Start date
Jul 31, 2011
Status verified
Jul 2019
Primary completion
Feb 29, 2012
Completion
Feb 29, 2012

Study Design

Enrollment
80 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Dysport and Xeomin
    30 U of Dysport® was injected on the right side of the forehead and 12 U Xeomin® was injected on the left side of the forehead (dose-equivalence 2.5:1).
  • Active Comparator: Xeomin and Dysport
    30 U Dysport® was injected on the left side of the forehead and 12 U Xeomin® was injected on the right side of the forehead (dose-equivalence 2.5:1).

Primary Outcome Measure

Percentage of Responders After 5 Months After the Procedure [ Time Frame: 5 months after intervention ]