Exploratory Lapatinib (Positron Emission Tomography) PET Study in Subjects With Breast Cancer
- Sponsor
- GlaxoSmithKline
- Study ID
- NCT01290354
- Phase
- PHASE1
- Status
- Completed
Conditions
- Cancer
Eligibility Criteria
- Sex
- FEMALE
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Lapatinib — DRUGUnlabelled, administered orally
- [11C] lapatinib — DRUGRadiolabelled, administered intravenously
Study Details
The purpose of this study is to find out how much lapatinib can enter both normal brains and brains in which tumours secondary to breast cancer have developed.
Key Dates
- Start date
- Sep 12, 2011
- Status verified
- Nov 2017
- Primary completion
- Mar 18, 2013
- Completion
- Mar 18, 2013
Study Design
- Enrollment
- 10 participants (actual)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- OTHER
Arms
- Experimental: lapatinibunlabelled, administered orally
Primary Outcome Measure
Brain penetration of [11C]lapatinib [ Time Frame: 8 days ]
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