Characterization of Human Memory Immune Responses to Prior Yellow Fever Vaccination

Part of paid clinical trials in Decatur, Georgia.

Sponsor
Emory University
Study ID
NCT01244802
Status
Enrolling By Invitation

Conditions

  • Yellow Fever Vaccine

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Study Details

The objective of this study is to study immune memory generated against the yellow fever (YFV) vaccine in participants who have previously received the vaccine. Volunteers will not receive vaccine shots; only immune responses to previous yellow fever vaccination will be studied. The study involves one or multiple blood draws.

Key Dates

Start date
Nov 30, 2010
Status verified
Nov 2024
Primary completion
Oct 31, 2029
Completion
Oct 31, 2029

Study Design

Enrollment
300 participants (estimated)

Arms

  • Arm: Group 1: 18 to 45 years of age
    Between the ages of 18 and 45 at the time of yellow fever vaccination
  • Arm: Group 2: 55 years of age and above
    Aged 55 or greater at the time of yellow fever vaccination

Primary Outcome Measure

Determine the phenotypic and functional characterization of memory T cell responses to YF vaccination [ Time Frame: Immune responses will be measured from at least 30 days after yellow fever vaccination. ]

Locations (1)

FacilityCityStateZIPSite coordinators
The Hope clinic of Emory Vaccine CenterDecaturGeorgia30030-

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The Hope clinic of Emory Vaccine Center· Decatur, GA