First Line Study of Irinotecan, Capecitabine and Oxaliplatin in Metastatic Gastric or Gastroesophageal Cancer.
- Sponsor
- AHS Cancer Control Alberta
- Study ID
- NCT01129310
- Phase
- PHASE2
- Status
- Completed
Conditions
- Gastric Adenocarcinoma
- Gastrointestinal Neoplasm
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Irinotecan-Capecitabine-Oxaliplatin — DRUGIrinotecan-160mg/m2 IV infusion over 60-90 min on Day 1 Capecitabine-1900mg/m2 daily PO in divided doses (=950mg/m2 BID) on days 2-15 Oxaliplatin- 100mg/m2 IV infusion over 2 hours Day 1
Study Details
The investigators hypothesize IXO chemotherapy will have an improvement in response rate and acceptable toxicity for uncurable metastatic gastric cancer compared to historical controls.
Key Dates
- Start date
- Jul 31, 2010
- Status verified
- Jan 2016
- Primary completion
- May 18, 2018
- Completion
- May 18, 2018
Study Design
- Enrollment
- 47 participants (actual)
- Allocation
- NON_RANDOMIZED
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Primary Outcome Measure
Overall Response Rate and dose limiting toxicity [ Time Frame: 2 years ]
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