Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease

Part of paid clinical trials in Murray, Utah.

Sponsor
University of Utah
Study ID
NCT01099982
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
13 Years - N/A
Healthy Volunteers
Not accepted

Study Details

Hypothesis: Tissue and serum samples collected from end-stage heart failure patients receiving left ventricular assist device implantation (LVAD) or heart transplantation will provide information regarding the basic science of heart disease. Tissue and serum samples collected from a limited numbers of "healthy controls" (donor grafts that were not utilized for heart transplantation) will serve as a comparator in research database projects. Design: This is a registry project; there are no investigational treatments, drug or procedures associated with participation in registry activities. This project is an organized functional data and tissue data gathering and storing (database) endeavor with specific focus on the functional, structural, and molecular aspects of heart failure. Data collection will not immediately influence the course of treatment for any patient.

Key Dates

Start date
Sep 30, 2008
Status verified
Jul 2025
Primary completion
Jan 31, 2028
Completion
Jan 31, 2028

Study Design

Enrollment
300 participants (estimated)

Arms

  • Arm: Advanced Heart Failure Therapy Group
    Patients diagnosed with end stage heart failure undergoing either VAD implantation or heart transplantation.
  • Arm: Normal Hearts Group
    Control samples will be obtained from individuals undergoing other types of cardiac surgery during which it is routine to discard some tissue intraoperatively.

Primary Outcome Measure

Change in myocardial function [ Time Frame: baseline and 3 months ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
Intermountain Medical CenterMurrayUtah84157
Abdallah Kfoury, M.D.
[email protected]
801-507-7000
University of Utah Health Sciences CenterSalt Lake CityUtah84132
Stavros Drakos, M.D, Ph.D
[email protected]
801-585-2340
VA Salt Lake City Health Care SystemSalt Lake CityUtah84148
Stavros Drakos, M.D, Ph.D
[email protected]
801-585-2340

Find similar trials in Murray, UT

By condition
Heart failure
By specialty
CardiologyHeart disease
By research site
Intermountain Medical Center· Murray, UTUniversity of Utah Health Sciences Center· Salt Lake City, UTVA Salt Lake City Health Care System· Salt Lake City, UT

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