Collecting and Analyzing Tissue Samples From Patients Undergoing Surgery for Non-Small Cell Lung Cancer

Part of paid clinical trials in Nashville, Tennessee.

Sponsor
Vanderbilt-Ingram Cancer Center
Study ID
NCT00897117
Status
Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 120 Years
Healthy Volunteers
Not accepted

Interventions

  • gene expression analysis — GENETIC
    Blood and lung tissue collection
  • microarray analysis — GENETIC
    Blood and lung tissue collection
  • protein expression analysis — GENETIC
    Blood and lung tissue collection
  • biologic sample preservation procedure — OTHER
    Blood and lung tissue collection
  • laboratory biomarker analysis — OTHER
    Blood and lung tissue collection
  • matrix-assisted laser desorption/ionization time of flight mass spectrometry — OTHER
    Blood and lung tissue collection

Study Details

RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that may occur in RNA and identify biomarkers related to cancer. PURPOSE: This research study is collecting and analyzing lung tissue samples from patients undergoing surgery for non-small cell lung cancer.

Key Dates

Start date
May 31, 2001
Status verified
Sep 2025
Primary completion
May 31, 2031
Completion
May 31, 2031

Study Design

Enrollment
4,000 participants (estimated)

Arms

  • Arm: Resectable non-small cell lung cancer
    Patients with clinical stage I or II invasive lung cancer that can be completely removed by surgery and who have not undergone chemotherapy or radiotherapy before surgery

Primary Outcome Measure

Protein and RNA expression fingerprints from collected samples [ Time Frame: after collection of designated samples ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
Dan Rudy Cancer Center at Saint Thomas HospitalNashvilleTennessee37205-
Vanderbilt-Ingram Cancer CenterNashvilleTennessee37232-6838
Clinical Trials Office - Vanderbilt-Ingram Cancer Center
800-811-8480
Veterans Affairs Medical Center - NashvilleNashvilleTennessee37212-

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