Mechanisms Underlying Impaired Diabetic Wound Healing

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
University of Pittsburgh
Study ID
NCT00777712
Status
Recruiting

Conditions

  • Non-healing Wound

Eligibility Criteria

Sex
ALL
Age
21 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • Blood draw — OTHER
    Blood will be drawn from subjects once and VAC sponge will be collected (which is normally discarded material per standard of care).

Study Details

The overall aim of this research is to utilize wound derived inflammatory cells from diabetic versus non diabetic human chronic wounds to understand mechanisms that are responsible for disregulated inflammation in individuals with diabetes. Biology of normal (peripheral blood derived cells) versus wound derived cells will also be studied.

Key Dates

Start date
Sep 1, 2008
Status verified
Jun 2026
Primary completion
Dec 31, 2029
Completion
Dec 31, 2030

Study Design

Enrollment
250 participants (estimated)

Arms

  • Arm: Chronic wound study
    Patients with diabetes or no diabetes

Primary Outcome Measure

Wound healing [ Time Frame: Week 16 ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
UPMC MontefiorePittsburghPennsylvania15219
CeCe Zamarripa, RN
412-647-7728
Piya Das Ghatak, PhD
4126240422
UPMC PresbyterianPittsburghPennsylvania15219
Cecilia Zamarripa, RN
412-647-7728
Piya Das Ghatak, PhD
412-648-8297

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