Mechanisms Underlying Impaired Diabetic Wound Healing
Part of paid clinical trials in Pittsburgh, Pennsylvania.
- Sponsor
- University of Pittsburgh
- Study ID
- NCT00777712
- Status
- Recruiting
Conditions
- Non-healing Wound
Eligibility Criteria
- Sex
- ALL
- Age
- 21 Years - 80 Years
- Healthy Volunteers
- Not accepted
Interventions
- Blood draw — OTHERBlood will be drawn from subjects once and VAC sponge will be collected (which is normally discarded material per standard of care).
Study Details
The overall aim of this research is to utilize wound derived inflammatory cells from diabetic versus non diabetic human chronic wounds to understand mechanisms that are responsible for disregulated inflammation in individuals with diabetes. Biology of normal (peripheral blood derived cells) versus wound derived cells will also be studied.
Key Dates
- Start date
- Sep 1, 2008
- Status verified
- Jun 2026
- Primary completion
- Dec 31, 2029
- Completion
- Dec 31, 2030
Study Design
- Enrollment
- 250 participants (estimated)
Arms
- Arm: Chronic wound studyPatients with diabetes or no diabetes
Primary Outcome Measure
Wound healing [ Time Frame: Week 16 ]
Central Contacts
- Piya Das Ghatak, PhD, MS412-648-8297
- Urmila Gnyawali4126240422
Locations (2)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| UPMC Montefiore | Pittsburgh | Pennsylvania | 15219 | |
| UPMC Presbyterian | Pittsburgh | Pennsylvania | 15219 |
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