Pharmacogenetic Determinants Of Treatment Response In Children

Part of paid clinical trials in Memphis, Tennessee.

Sponsor
St. Jude Children's Research Hospital
Study ID
NCT00730678
Status
Recruiting
Apply to this trial

Conditions

  • All Malignancies
  • Children Being Treated for Catastrophic Illness

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Accepted

Study Details

To investigate whether genetic polymorphisms in genes encoding proteins involved in the metabolism or effects of drugs or environmental agents influence the disposition or effects of these xenobiotic substrates. To investigate the nature of heritability and the genetic basis of pharmacogenetic traits by studying family members of individuals with specific genotypes.

Key Dates

Start date
Aug 17, 1998
Status verified
Apr 2026
Primary completion
Dec 31, 2033
Completion
Mar 31, 2034

Study Design

Enrollment
8,800 participants (estimated)

Arms

  • Arm: All Participants
    All participants enrolled on this study will have blood drawn for genetic testing.

Primary Outcome Measure

To investigate whether genetic polymorphisms in genes encoding proteins involved in the metabolism or effects of drugs or environmental agents influence the disposition or effects of these xenobiotic substrates. [ Time Frame: 28 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
St. Jude Children's Research HospitalMemphisTennessee38105
Jun J. Yang, Ph. D.
[email protected]
888-226-4343
Jun J. Yang, Ph. D. (PRINCIPAL_INVESTIGATOR)
Kristine Crews, PharmD, MSCI (PRINCIPAL_INVESTIGATOR)

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St. Jude Children's Research Hospital· Memphis, TN