Combined Immunochemotherapy Followed By Reduced Dose Radiation Therapy (RT) for Patients With Newly Diagnosed Primary Central Nervous System Lymphoma
Part of paid clinical trials in New York, New York.
- Sponsor
- Memorial Sloan Kettering Cancer Center
- Study ID
- NCT00594815
- Status
- Completed
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- N/A - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Cytarabine, Leucovorin, Methotrexate, Procarbazine, Rituximab, Vincristine — DRUGImmunochemotherapy
Study Details
The purpose of this study is to find out if immunotherapy (rituximab) added to chemotherapy is a safe treatment for primary central nervous system lymphoma (PCNSL). PCNSL is a rare tumor. It is usually treated with chemotherapy and radiation. This combination prolongs survival, but about half of patients relapse. The investigators hope that the addition of rituximab will improve the control of the tumor.
Key Dates
- Start date
- Aug 28, 2002
- Status verified
- Apr 2017
- Primary completion
- Feb 23, 2016
- Completion
- Feb 23, 2016
Study Design
- Enrollment
- 52 participants (actual)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: 1
Primary Outcome Measure
Total Number of Participants Who Experienced Acute Treatment Related Adverse Events [ Time Frame: 2 years ]
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | - |
Find similar trials in New York, NY
By research site
Related Studies
- Ascertainment of Families for Genetic Studies of Familial Lymphoproliferative DisordersRecruiting · Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey
- Longitudinal Sexual and Reproductive Health Study of Women With Breast Cancer and LymphomaRecruiting · Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey
- A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)PHASE1/PHASE2 · Recruiting · Merck Sharp & Dohme LLC · Aurora, Colorado
- Study of Ruxolitinib in Relapsed or Refractory T or NK Cell LymphomaPHASE2 · Recruiting · Memorial Sloan Kettering Cancer Center · Miami, Florida