Barrett's Esophagus Related Neoplasia (BERN) Project

Part of paid clinical trials in Kansas City, Missouri.

Sponsor
Midwest Biomedical Research Foundation
Study ID
NCT00590239
Status
Recruiting
Apply to this trial

Conditions

  • Barrett's Esophagus
  • Gastroesophageal Reflux
  • Neoplasms

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

* The use of high resolution endoscopy (HRE), narrow band imaging (NBI) and chromoendoscopy increases the detection rates of Barrett's esophagus (BE) and early neoplasia. * Endoscopic mucosal resection (EMR) will improve the accuracy for detection of dysplasia/early neoplasia. Specific Aim 1 - To create a video-atlas of non-dysplastic and dysplastic/early neoplastic lesions in patients with BE. This will be used for training purposes and to assess learning curve associated with these new technologies. Specific Aim 2 - To create a standardized classification system for the mucosal and vascular patterns observed in patients with BE. Specific Aim 3 - To determine the interobserver agreement using the video-atlas for the mucosal and vascular patterns classification agreed upon. Specific Aim 4 - To determine the endoscopic detection rate of esophageal cancer or precancerous lesions removed during endoscopy. Specific Aim 5 - To determine the pathologic and clinical outcomes of patients undergoing EMR/ablation; including morbidity, mortality and complications of the procedure. Results to date (June 2008) : this study is active and open to enrollment. Currently 26 patients have enrolled in this study at the Kansas City VA medical center. In order to participate, patients must be eligible for care at the KCVA hospital.

Key Dates

Start date
May 15, 2007
Status verified
Nov 2024
Primary completion
Nov 1, 2026
Completion
Dec 30, 2026

Study Design

Enrollment
150 participants (estimated)

Primary Outcome Measure

Video-atlas creation [ Time Frame: March 2007 - June 2016 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Kansas city VA Medical centerKansas CityMissouri64128
April Higbee, RN
[email protected]
816-861-4700
Amit Rastogi, MD (SUB_INVESTIGATOR)
Ajay Bansal, MD (SUB_INVESTIGATOR)
Prateek Sharma, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Kansas City, MO

By research site
Kansas city VA Medical center· Kansas City, MO

Related Studies