Intraocular Lens Power Calculation After Laser Refractive Surgery Based on Optical Coherence Tomography

Part of paid clinical trials in Portland, Oregon.

Sponsor
Oregon Health and Science University
Study ID
NCT00532051
Status
Recruiting
Apply to this trial

Conditions

  • Cataract

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • OCT measurements — DEVICE
    This study is about a new imaging method to study the front part of the eye. This imaging method is called Optical Coherence Tomography (OCT) which provides detailed cross-sectional (layered) views of structures in the eye. The OCT system scans a beam of light across the eye to take a picture. OCT provides a more detailed image than other imaging methods of the eye such as ultrasound, CT scan (computed tomography), and MRI (magnetic resonance imaging). In addition, OCT imaging does not touch the eye. OCT is routinely used in imaging structures in the back of the eye (retina) and cornea. This study uses high-speed FDA approved OCT systemsThe measurements from the OCT systems are used in selecting IOL power.

Study Details

The long-term goal of this project is to utilize very high-speed optical coherence tomography (OCT) technology to guide surgical treatments of corneal diseases. OCT is well known for its exquisite resolution, but until recently it has not had sufficient speed to capture the shape of the cornea because of eye motion during OCT scanning. The development of Fourier-domain (FD) OCT technology has made the requisite speed possible. The objective of this project is to develop methods for imaging the cornea with an FD-OCT system that will precisely measure corneal shape and use this information to guide surgery. Cataract surgery in patients with previous laser vision correction often leads to significant near- or far-sightedness, a problem that could be resolved by using a more accurate intraocular lens power selection formula based on the measurement of corneal refractive power with OCT.

Key Dates

Start date
Apr 30, 2011
Status verified
Feb 2024
Primary completion
Jul 31, 2026
Completion
Jul 31, 2026

Study Design

Enrollment
690 participants (estimated)

Primary Outcome Measure

IOL power prediction (baseline visit) [ Time Frame: Study enrollment ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Casey Eye Institute, Oregon Health & Science UniversityPortlandOregon97239
Humberto Martinez, COT
[email protected]
503-494-7712
Denny Romfh, OD
[email protected]
503-494-4351
David Huang, MD, PhD (PRINCIPAL_INVESTIGATOR)
Winston Chamberlain, MD, PhD (SUB_INVESTIGATOR)
Afshan Nanji, MD (SUB_INVESTIGATOR)
Seema Gupta, MD (SUB_INVESTIGATOR)
Ellen Davis, MD (SUB_INVESTIGATOR)
Yan Li, PhD (SUB_INVESTIGATOR)
Richard Stutzman, MD (SUB_INVESTIGATOR)

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Casey Eye Institute, Oregon Health & Science University· Portland, OR

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