Post-operative Radiation With IMRT in the Management of Stage IIB-III Breast Cancer

Sponsor
Ottawa Hospital Research Institute
Study ID
NCT00508352
Status
Completed

Conditions

Eligibility Criteria

Sex
FEMALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Helical tomotherapy IMRT — PROCEDURE
    Helical tomotherapy IMRT 50 Gy in 25 fractions, daily treatment

Study Details

Research has shown that treatment with conventional radiation techniques and chemotherapy following mastectomy or breast conserving surgery has resulted in better rates of locoregional control and overall survival in stage IIB-III breast cancer. The current feasibility trial using the most recent advance in radiation therapy, namely helical tomotherapy intensity modulated radiation therapy (HT-IMRT), hopes to improve on the results of conventional radiation by decreasing the amount of radiation-induced toxicity in patients with stage IIb-III breast cancer.

Key Dates

Start date
Jan 31, 2007
Status verified
May 2025
Primary completion
Oct 31, 2009
Completion
Oct 31, 2009

Study Design

Enrollment
30 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Helical tomotherapy
    Helical tomotherapy IMRT 50 Gy in 25 fractions, daily treatment

Primary Outcome Measure

Acute Radiation Effects (Less Than 90 Days Post Treatment) [ Time Frame: less than 90 days post treatment ]

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