Vinorelbine and Bevacizumab in Treating Older Patients With Stage III or Stage IV Non-Small Cell Lung Cancer
Part of paid clinical trials in Rochester, New York.
- Sponsor
- University of Rochester
- Study ID
- NCT00309998
- Phase
- PHASE2
- Status
- Completed
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 70 Years - 120 Years
- Healthy Volunteers
- Not accepted
Interventions
- bevacizumab — BIOLOGICAL
- vinorelbine tartrate — DRUG
Study Details
RATIONALE: Drugs used in chemotherapy, such as vinorelbine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. Giving vinorelbine together with bevacizumab may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving vinorelbine together with bevacizumab works in treating older patients with stage III or stage IV non-small cell lung cancer.
Key Dates
- Start date
- Sep 30, 2005
- Status verified
- Oct 2024
- Primary completion
- May 31, 2007
Study Design
- Enrollment
- 50 participants (estimated)
- Primary purpose
- TREATMENT
Primary Outcome Measure
Median time to disease progression by imaging study every 6 weeks
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| James P. Wilmot Cancer Center at University of Rochester Medical Center | Rochester | New York | 14642-0001 | - |
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