Phase II Iressa Versus Vinorelbine (INVITE)
- Sponsor
- AstraZeneca
- Study ID
- NCT00256711
- Phase
- PHASE2
- Status
- Completed
Conditions
- Non-Small-Cell Lung Carcinoma
Eligibility Criteria
- Sex
- ALL
- Age
- 70 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Gefitinib — DRUG
- Vinorelbine — DRUG
Study Details
This is a randomized, open label, parallel group, multi-centre, phase II study of progression free survival, comparing oral ZD1839 (IRESSA™) (250 mg tablet once daily) to vinorelbine 30 mg/m2 infusion on days 1 and 8 of a 21-day cycle) in chemonaïve, elderly patients with locally advanced (stage IIIB) or metastatic (stage IV) non-small cell lung cancer.
Key Dates
- Start date
- Jul 31, 2004
- Status verified
- Apr 2009
- Completion
- Feb 28, 2006
Study Design
- Enrollment
- 192 participants
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Primary Outcome Measure
To compare ZD1839 and vinorelbine in terms of progression free survival
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