Vinorelbine, Gemcitabine, and Docetaxel Compared With Paclitaxel and Carboplatin in Treating Patients With Advanced Non-Small Cell Lung Cancer

Sponsor
Japan Multinational Trial Organization
Study ID
NCT00079287
Phase
PHASE3
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • carboplatin — DRUG
  • docetaxel — DRUG
  • gemcitabine hydrochloride — DRUG
  • paclitaxel — DRUG
  • vinorelbine tartrate — DRUG

Study Details

RATIONALE: Drugs used in chemotherapy, such as vinorelbine, gemcitabine, docetaxel, paclitaxel, and carboplatin, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which combination chemotherapy regimen is more effective in treating non-small cell lung cancer. PURPOSE: This randomized phase III trial is studying how well giving vinorelbine together with gemcitabine and docetaxel works compared to giving paclitaxel together with carboplatin in treating patients with stage IIIB, stage IV, or recurrent non-small cell lung cancer.

Key Dates

Start date
Mar 31, 2001
Status verified
Apr 2005
Completion
Nov 30, 2008

Study Design

Allocation
RANDOMIZED
Primary purpose
TREATMENT

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