Active Symptom Control With or Without Chemotherapy in Treating Patients With Malignant Pleural Mesothelioma

Sponsor
Medical Research Council
Study ID
NCT00075699
Phase
PHASE3
Status
Completed

Conditions

  • Malignant Mesothelioma

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • cisplatin — DRUG
  • mitomycin C — DRUG
  • vincristine sulfate — DRUG
  • vinorelbine tartrate — DRUG
  • pain therapy — PROCEDURE
  • psychosocial assessment and care — PROCEDURE
  • quality-of-life assessment — PROCEDURE

Study Details

RATIONALE: Active symptom control may decrease chest pain, breathlessness, sweating, and general discomfort in patients with malignant pleural mesothelioma. It is not yet known if active symptom control is more effective with or without chemotherapy. PURPOSE: This randomized phase III trial is studying active symptom control and chemotherapy to see how well they work compared to active symptom control alone in treating patients with malignant pleural mesothelioma.

Key Dates

Start date
Sep 30, 2003
Status verified
Jun 2008

Study Design

Enrollment
840 participants (estimated)
Allocation
RANDOMIZED
Primary purpose
TREATMENT

Primary Outcome Measure

Overall survival

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