Pixantrone, Cytarabine, Methylprednisolone, and Cisplatin in Treating Patients With Aggressive Non-Hodgkin's Lymphoma in First Relapse

Part of paid clinical trials in Tucson, Arizona.

Sponsor
Theradex
Study ID
NCT00069966
Phase
PHASE2
Status
Unknown

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • filgrastim — BIOLOGICAL
  • rituximab — BIOLOGICAL
  • cisplatin — DRUG
  • cytarabine — DRUG
  • methylprednisolone — DRUG
  • pixantrone dimaleate — DRUG
  • autologous bone marrow transplantation — PROCEDURE
  • peripheral blood stem cell transplantation — PROCEDURE

Study Details

RATIONALE: Drugs used in chemotherapy, such as pixantrone, cytarabine, methylprednisolone, and cisplatin, work in different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating patients who have relapsed aggressive non-Hodgkin's lymphoma.

Key Dates

Start date
Apr 30, 2003
Status verified
Nov 2004

Study Design

Primary purpose
TREATMENT

Locations (28)

FacilityCityStateZIPSite coordinators
Arizona Oncology Associates - Craycroft Road OfficesTucsonArizona85712-2254-
City of Hope Comprehensive Cancer CenterDuarteCalifornia91010-3000-
USC/Norris Comprehensive Cancer Center and HospitalLos AngelesCalifornia90033-0804-
Rocky Mountain Cancer Centers - Colorado SpringsColorado SpringsColorado80933-1181-
Rocky Mountain Cancer Centers - Denver MidtownDenverColorado80218-
Delaware Clinical & Laboratory PhysiciansNewarkDelaware19713-
Pasco, Hernando Oncology Associates, P.A.New Port RicheyFlorida34652-
Hematology-Oncology Associates of IllinoisChicagoIllinois60611-2998-
Markey Cancer Center at University of Kentucky Chandler Medical CenterLexingtonKentucky40536-0084-
Louisiana State University Health Sciences Center - ShreveportShreveportLouisiana71130-3932-
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer InstituteBostonMassachusetts02115-
Massachusetts General Hospital Cancer CenterBostonMassachusetts02114-
UNMC Eppley Cancer Center at the University of Nebraska Medical CenterOmahaNebraska68198-7680-
North Shore University HospitalManhassetNew York11030-
SUNY Upstate Medical University HospitalSyracuseNew York13210-
Duke Comprehensive Cancer CenterDurhamNorth Carolina27710-
Piedmont Hematology-Oncology AssociatesWinston-SalemNorth Carolina27103-
Gabrail Cancer Center - Canton OfficeCantonOhio44718-
Cleveland Clinic Taussig Cancer CenterClevelandOhio44195-
Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve UniversityClevelandOhio44106-5055-
Cancer Care Associates-WestOklahoma CityOklahoma73112-4414-
Providence Cancer Center at Providence Portland Medical CenterPortlandOregon97213-
Penn State Cancer Institute at Milton S. Hershey Medical CenterHersheyPennsylvania17033-0850-
Cancer Centers of the Carolinas - EastsideGreenvilleSouth Carolina29615-
Baylor University Medical CenterDallasTexas75246-
University of Texas - MD Anderson Cancer CenterHoustonTexas77030-
Fairfax Northern Virginia Hematology Oncology, P.C. - FairfaxFairfaxVirginia22031-
Medical College of Wisconsin Cancer CenterMilwaukeeWisconsin53226-3596-

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