Combination Chemotherapy in Treating Patients With Colorectal Cancer

Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Study ID
NCT00039208
Phase
PHASE2
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving drugs at the time of day that allows for the best drug response may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Randomized phase II trial to determine the best time to give irinotecan combined with fluorouracil, leucovorin, and oxaliplatin in treating patients who have colorectal cancer.

Key Dates

Start date
Feb 28, 2002
Status verified
Jul 2012
Primary completion
Aug 31, 2005

Study Design

Allocation
RANDOMIZED
Primary purpose
TREATMENT

Primary Outcome Measure

Peak delivery time for CPT11 tolerability over the first 3 courses of treatment in patients who started therapy

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