Combination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655)

Part of paid clinical trials in Tucson, Arizona.

Sponsor
American College of Radiology Imaging Network
Study ID
NCT00023868
Phase
PHASE3
Status
Terminated

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 120 Years
Healthy Volunteers
Not accepted

Interventions

  • FOLFIRI regimen — DRUG
  • cisplatin — DRUG
  • doxorubicin hydrochloride — DRUG
  • fluorouracil — DRUG
  • irinotecan hydrochloride — DRUG
  • leucovorin calcium — DRUG
  • mitomycin C — DRUG

Study Details

RATIONALE: Drugs used in chemotherapy, such as irinotecan, fluorouracil, and leucovorin, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping the cells from dividing. Chemoembolization kills tumor cells by blocking the blood flow to the tumor and keeping chemotherapy drugs near the tumor. It is not yet known if chemoembolization is more effective than standard chemotherapy in treating metastatic cancer. PURPOSE: This phase I trial and randomized phase III trial is studying the effectiveness of chemoembolization in treating patients who have colorectal cancer metastatic to the liver.

Key Dates

Start date
Nov 1, 2001
Status verified
Nov 2020
Primary completion
Sep 25, 2002
Completion
Sep 25, 2002

Study Design

Allocation
RANDOMIZED
Primary purpose
TREATMENT

Locations (9)

FacilityCityStateZIPSite coordinators
Arizona Cancer CenterTucsonArizona85724-
H. Lee Moffitt Cancer Center and Research InstituteTampaFlorida33612-9497-
Robert H. Lurie Comprehensive Cancer Center, Northwestern UniversityChicagoIllinois60611-3013-
Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsBaltimoreMaryland21231-2410-
Beth Israel Deaconess Medical CenterBostonMassachusetts02215-
NYU School of Medicine's Kaplan Comprehensive Cancer CenterNew YorkNew York10016-
State University of New York - Upstate Medical UniversitySyracuseNew York13210-
University of Pennsylvania Cancer CenterPhiladelphiaPennsylvania19104-4283-
University of Texas - MD Anderson Cancer CenterHoustonTexas77030-4009-

Find similar trials in Tucson, AZ

By condition
Colorectal cancer
By specialty
OncologyGI oncology
By research site
Arizona Cancer Center· Tucson, AZH. Lee Moffitt Cancer Center and Research Institute· Tampa, FLRobert H. Lurie Comprehensive Cancer Center, Northwestern University· Chicago, ILSidney Kimmel Comprehensive Cancer Center at Johns Hopkins· Baltimore, MDBeth Israel Deaconess Medical Center· Boston, MANYU School of Medicine's Kaplan Comprehensive Cancer Center· New York, NY

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