Irinotecan Followed by Radiation Therapy and Temozolomide in Treating Children With Newly Diagnosed Brain Tumor
Part of paid clinical trials in Memphis, Tennessee.
- Sponsor
- St. Jude Children's Research Hospital
- Study ID
- NCT00004068
- Phase
- PHASE2
- Status
- Completed
Conditions
- Brain and Central Nervous System Tumors
Eligibility Criteria
- Sex
- ALL
- Age
- 3 Years - 21 Years
- Healthy Volunteers
- Not accepted
Interventions
- irinotecan hydrochloride — DRUG
- temozolomide — DRUG
- conventional surgery — PROCEDURE
- radiation therapy — RADIATION
Study Details
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of irinotecan followed by radiation therapy and temozolomide in treating children who have newly diagnosed brain tumor.
Key Dates
- Start date
- Mar 31, 1999
- Status verified
- Oct 2011
- Primary completion
- Apr 30, 2003
- Completion
- Apr 30, 2003
Study Design
- Enrollment
- 53 participants (actual)
- Primary purpose
- TREATMENT
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Saint Jude Children's Research Hospital | Memphis | Tennessee | 38105-2794 | - |
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