Surgery With or Without Preoperative Chemotherapy in Treating Patients With Resectable Non-small Cell Lung Cancer

Sponsor
Medical Research Council
Study ID
NCT00003159
Phase
PHASE3
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Interventions

  • carboplatin — DRUG
  • cisplatin — DRUG
  • docetaxel — DRUG
  • gemcitabine hydrochloride — DRUG
  • ifosfamide — DRUG
  • mitomycin C — DRUG
  • paclitaxel — DRUG
  • vinblastine sulfate — DRUG
  • vinorelbine tartrate — DRUG
  • conventional surgery — PROCEDURE
  • neoadjuvant therapy — PROCEDURE

Study Details

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if surgery is more effective with or without preoperative chemotherapy in treating non-small cell lung cancer. PURPOSE: This randomized phase III trial is studying surgery and preoperative chemotherapy to see how well they work compared to surgery alone in treating patients with resectable non-small cell lung cancer.

Key Dates

Start date
Aug 31, 1997
Status verified
May 2005
Completion
Jun 30, 2007

Study Design

Enrollment
600 participants (estimated)
Allocation
RANDOMIZED
Primary purpose
TREATMENT

Primary Outcome Measure

Survival

Related Studies