Omaha, NE Clinical Trials Report — May 2026

For individuals in Omaha, NE, considering participation in clinical research, May 2026 brings both urgent opportunities and significant new studies, particularly in cancer research. Omaha currently hosts 581 clinical trials actively recruiting participants across 219 research facilities, offering diverse avenues to contribute to medical advancements.

This month, a notable Phase 3 drug trial from a major sponsor has opened its doors in Omaha, focusing on advanced prostate cancer. AstraZeneca is sponsoring NCT07611110, "AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)." This important study aims to enroll 670 participants globally, evaluating AZD2265 against current standard treatments to demonstrate superiority in radiographic progression-free survival and overall survival for individuals with metastatic castration-resistant prostate cancer.

Act Now: Trials Nearing Their Close

Time is of the essence for those interested in trials with impending deadlines. A total of 22 clinical trials in Omaha are slated to conclude enrollment within the next 90 days. This includes opportunities for healthy volunteers, with 3 trials still seeking participants without specific health conditions before their windows close.

Patients with certain health conditions should also note the trials closing soon. Conditions with limited time remaining for enrollment include:

• Heart failure (2 trials)
• Benign prostatic hyperplasia (BPH)
• Diabetic foot ulcer (DFU)
• Castration resistant metastatic prostate cancer
• Colorectal cancer
• COVID-19
• Cancer harboring BRAF alterations
• Hearing loss, sensorineural
• Atrial fibrillation
• Heart transplant

New Research Opportunities Emerge

Omaha welcomed 5 new clinical trials this month, a decrease compared to the 9 new trials that opened in April 2026. These new studies are exploring a range of conditions and treatment types:

• Metastatic castration-resistant prostate cancer
• Metastatic prostate cancer
• Ovarian cancer
• Prostate adenocarcinoma
• Prostate cancer
• SPO2 (peripheral oxygen saturation) measurement validation
• SPO2

The new trials are primarily industry-sponsored, with 4 studies funded by industry and 1 by another entity. Notable sponsors include AstraZeneca, GE Healthcare, University of Nebraska, and Xencor, Inc. In terms of trial type, there are 2 new drug trials, 1 biological trial, 1 device trial, and 1 radiation trial.

Omaha's Leading Research Facilities

Omaha's robust clinical research landscape is supported by several key institutions that consistently lead in the number of active trials. These facilities are central to the city's contributions to medical science:

• University of Nebraska Medical Center (211 trials)
• Alegent Health Bergan Mercy Medical Center (43 trials)
• Nebraska Medicine-Village Pointe (40 trials)
• Creighton University Medical Center (38 trials)
• Alegent Health Lakeside Hospital (37 trials)
• Alegent Health Immanuel Medical Center (37 trials)
• Nebraska Cancer Specialists (36 trials)
• Nebraska Methodist Hospital (33 trials)
• Children's Hospital and Medical Center of Omaha (29 trials)
• Research Site (23 trials)
• Nebraska Cancer Specialists/Oncology Hematology West PC - MECC (20 trials)
• Oncology Associates PC (16 trials)

The University of Nebraska Medical Center stands out as the city's largest research hub, while specialized centers like Nebraska Cancer Specialists and Children's Hospital and Medical Center of Omaha contribute significantly to specific areas of medicine.

Diverse Participation and Healthy Volunteer Opportunities

Clinical trials in Omaha are open to a wide range of participants. Of the new trials launched this month, 1 trial includes children, 1 is female-only, 3 are male-only, and 4 include older adults. This ensures diverse populations can contribute to research efforts.

For individuals without a specific medical condition, opportunities to participate as a healthy volunteer are available. While none of the 5 new trials this month are seeking healthy volunteers, there are still 48 total trials actively recruiting healthy participants across Omaha. Those interested in contributing to medical research without a diagnosed condition should explore these options, especially the 3 healthy volunteer trials closing soon.

Expanding Your Search Beyond Omaha

While Omaha offers a comprehensive array of clinical trial opportunities, individuals in Nebraska may also find options in nearby cities. Lincoln, for example, currently has 2 clinical trials actively recruiting participants.

As spring progresses, Omaha's clinical research community continues to advance medical knowledge, providing valuable opportunities for patients and healthy volunteers to play a direct role in shaping the future of healthcare.