Oklahoma City, OK Clinical Trials Report — April 2026

For Oklahoma City residents exploring clinical trial options, April 2026 presents a critical window to join studies before enrollment closes. A total of 41 trials are slated to conclude within the next 90 days, with 1 of these still actively seeking healthy volunteers. Individuals interested in contributing to medical advancements, especially those without specific health conditions, should explore these options promptly.

Urgent Opportunities: Trials Closing Soon

Patients managing certain health conditions also face impending deadlines to join research. Trials focused on various cancers and inflammatory conditions are among those with limited time remaining for enrollment. Conditions with trials closing soon include:

• Stage IV lung cancer AJCC V8
• Metastatic malignant solid neoplasm
• Recurrent endometrial carcinoma
• Stage IV pancreatic cancer AJCC V8
• Stage III pancreatic cancer AJCC V8
• Primary peritoneal cancer
• Cancer weight loss
• Cancer survivorship
• Aged
• Colitis, ulcerative

While the majority of these closing trials are for specific patient populations, the single trial accepting healthy volunteers offers a unique chance for broad participation before its window closes.

New Research Opportunities in Oklahoma City

This month, Oklahoma City saw the launch of 3 new clinical trials, matching the number of new trials opened in March 2026. This brings the city's total to 618 clinical trials currently recruiting across 248 research facilities.

Among the new additions are notable Phase 2 studies from major sponsors and local institutions:

• A significant Phase 2 study, NCT07525375, sponsored by AstraZeneca, is investigating lung function in children aged 4 to less than 12 years with asthma. This trial aims to evaluate the effect of two different doses of inhaled glycopyrronium as an add-on treatment.
• Another important Phase 2 trial, NCT07534332, led by the University of Oklahoma, is exploring "Disulfiram in Rheumatoid Arthritis." This study focuses on the chronic autoimmune disease and its connection to obesity, which can impact disease activity and treatment response.

New trials this month are exploring a range of conditions, including asthma, elbow fractures, inflammation, obesity, and rheumatoid arthritis. Of the new trials, 1 is accepting healthy volunteers, adding to the 39 total trials currently recruiting healthy participants across Oklahoma City. This provides numerous avenues for those interested in supporting medical research without a specific medical condition.

Oklahoma City's Leading Research Hubs

Oklahoma City is home to several prominent research institutions that consistently run a high volume of clinical trials. These facilities are key destinations for individuals seeking to participate in medical research:

• University of Oklahoma Health Sciences Center (202 trials)
• Mercy Hospital Oklahoma City (57 trials)
• University of Oklahoma (27 trials)
• OU Health Stephenson Cancer Center (18 trials)
• Stephenson Cancer Center (16 trials)
• Research Site (15 trials)
• Oklahoma Medical Research Foundation (13 trials)
• Hightower Clinical (11 trials)
• The University of Oklahoma Health Sciences Center (11 trials)
• Oklahoma Heart Hospital (9 trials)

These institutions offer a broad spectrum of research, from comprehensive medical studies at the University of Oklahoma Health Sciences Center to specialized oncology research at OU Health Stephenson Cancer Center and cardiovascular studies at Oklahoma Heart Hospital.

Participation and Demographics

Participation in clinical trials is open to a diverse range of individuals. Of the 3 new trials launched this month, 2 are designed to include children, and 1 includes older adults, ensuring that various age groups have opportunities to contribute to medical science. Academic institutions, notably the University of Oklahoma, and industry sponsors like AstraZeneca, are driving the new research efforts in the city.

Expanding Your Search: Nearby Options

While Oklahoma City offers a robust selection of clinical trial opportunities, individuals may also find options in nearby communities within Oklahoma. For instance, Tahlequah currently has 1 trial recruiting, providing an additional avenue for those looking to participate in medical research within the state.

As we move further into spring, the focus will remain on the ongoing enrollment in these significant studies and the continued exploration of new therapeutic strategies, with Oklahoma City's dedicated research community at the forefront of medical innovation.