ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
for Breast Neoplasms
Drug: Pumitamig
26 locations incl. Springdale
Sponsor: BioNTech SE
Sex: All·Age: 18+
Code: NCT07173751·Phase 3·Recruiting
Breast oncology Clinical Trials in Urbana, IL
As of June 2026, 16 paid clinical trials are recruiting for Breast oncology in Urbana, Illinois. Breast oncology research tests new hormone therapies, HER2-targeted agents, PARP inhibitors, antibody-drug conjugates, and immunotherapy combinations across early-stage and metastatic disease. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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16 clinical trials for Breast oncology
·Clear filters·↓ Download CSVE-Mindfulness Approaches for Living After Breast Cancer
for Breast Cancer
332 locations incl. Phoenix
Sponsor: NRG Oncology
Sex: All·Age: 18 - 50
Code: NCT06748222·Phase 3·Recruiting
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
for Breast Cancer
51 locations incl. Phoenix
Sponsor: Hoffmann-La Roche
Sex: All·Age: 18+
Code: NCT06790693·Phase 3·Recruiting
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
for Breast Carcinoma
464 locations incl. Fairbanks
Sponsor: Wake Forest University Health Sciences
Sex: All·Age: 18+
Code: NCT06418204·Recruiting
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
for Anatomic Stage IV Breast Cancer AJCC v8
256 locations incl. Tucson
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT06500455·Phase 3·Recruiting
Study to Assess the Ability of the Portable Scalp Cooling System (PSCS) to Prevent Hair Loss
for Alopecia
2 locations incl. Tucson
Sponsor: Cooler Heads Care Inc.
Sex: Female·Age: 21+
Code: NCT05484973·Recruiting
Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer
for Advanced Breast Cancer
Drug: Camizestrant
54 locations incl. Gilbert
Sponsor: AstraZeneca
Sex: All·Age: 18+
Code: NCT06380751·Phase 3·Recruiting
Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors
for Breast Cancer
673 locations incl. Anchorage
Sponsor: NRG Oncology
Sex: All·Age: 18 - 100
Code: NCT05896189·Recruiting
Mobile Health for Adherence in Breast Cancer Patients
for Anatomic Stage IV Breast Cancer AJCC v8
499 locations incl. Fairbanks
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT06112613·Recruiting
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
for Breast Cancer
79 locations incl. Phoenix
Sponsor: BriaCell Therapeutics Corporation
Sex: All·Age: 18+
Code: NCT06072612·Phase 3·Recruiting
OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer
for Breast Cancer
Drug: Palazestrant
47 locations incl. Tucson
Sponsor: Olema Pharmaceuticals, Inc.
Sex: All·Age: 18+
Code: NCT06016738·Phase 3·Recruiting
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
for Breast Cancer
1208 locations incl. Birmingham
Sponsor: NRG Oncology
Sex: Female·Age: 18 - 60
Code: NCT05879926·Phase 3·Recruiting
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
for Triple Negative Breast Cancer
184 locations incl. Birmingham
Sponsor: Gilead Sciences
Sex: All·Age: 18+
Code: NCT05633654·Phase 3·Recruiting
Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
for Breast Neoplasms
11 locations incl. Fullerton
Sponsor: Stemline Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT05386108·Phase 1, Phase 2·Recruiting
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
for Acute Lymphoblastic Leukemia
746 locations incl. Anchorage
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 40 - 75·Accepts healthy volunteers
Code: NCT05334069·Recruiting
Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer
for Breast Cancer
451 locations incl. Fairbanks
Sponsor: Canadian Cancer Trials Group
Sex: Female·Age: 35+
Code: NCT03488693·Phase 3·Recruiting
About research studies in Urbana
Urbana has approximately 152 recruiting research studies across a wide range of therapeutic areas. Illinois's research base includes Northwestern Medicine, Rush University Medical Center, University of Chicago Medicine, and Ann & Robert H. Lurie Children's Hospital, covering oncology, cardiology, and pediatric specialties.
Top Research Study Locations in Urbana
Researchers run research studies in Urbana, IL at 23 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Carle Cancer Center | Stage IV Lung Cancer AJCC v8, Malignant Solid Neoplasm, Breast Cancer | 119 |
| The Carle Foundation Hospital | Metastatic Malignant Neoplasm in the Brain, Stage IV Renal Cell Cancer AJCC v8, Metastatic Renal Cell Carcinoma | 35 |
| Carle Foundation Hospital | Cardiovascular Diseases, Clostridium Difficile Infection, Coronary Artery Disease | 7 |
| Freer Hall - University of Illinois | Control Condition, Glucose Metabolism, Obese Patients (BMI ≥ 30 kg/m²) | 2 |
| University of Illinois | Healthy Children, Tick Bites | 2 |
| University of Illinois Urbana-Champaign | Adults, Cognitive Change, EEG | 2 |
| University of Illinois at Urbana-Champaign | Aging, Cognitive Change, Diet, Healthy | 2 |
| Louise Freer Hall | Isotope Labeling, Muscle Health, Muscle Protein Synthesis | 1 |
| Carle Cancer Center NCI Community Oncology Research Program | Locally Advanced Hepatocellular Carcinoma, Metastatic Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8 | 1 |
| Carle Cancer Institute | Carcinoma, Non-Small Cell Lung | 1 |
| Carle Founation Hospital | Epidermal Growth Factor Receptor Gene Mutation, Non Small Cell Lung Cancer, Stage III Lung Cancer | 1 |
| Carle Foundation Cancer Institute-Urbana | Breast Cancer, Breast Cancer Metastatic, Breast Neoplasm | 1 |
| Carle Foundation Hosp | Lumbar Spinal Stenosis | 1 |
| Carle Foundation Hospital d/b/a Carle Cancer Center | Breast Neoplasms | 1 |
| Carle Foundation Hospital, NeuroScience Institute | Degenerative Disc Disease, Spinal Stenosis | 1 |
| Carle Health | Alopecia, Breast Cancer, Chemotherapy-induced Alopecia | 1 |
| Clinical Trial Site | Advanced Breast Cancer, Breast Cancer, ER Positive Breast Cancer | 1 |
| Disability Participation and Quality of Life (DPQOL) Laboratory | Multiple Sclerosis, Spinal Cord Injuries (SCI) | 1 |
| Local Institution - 0423 | Non-Small Cell Lung Cancer (NSCLC) | 1 |
| OSF Heart of Mary Medical Center | Lumbar Spinal Stenosis | 1 |
| TG Therapeutics Investigational Trial Site | Multiple Sclerosis, Relapsing Multiple Sclerosis | 1 |
| University of Illinois Extension | Relational Problems, Relationships, Marital | 1 |
| University of Illinois at Urbana Champaign | Sleeve Gastrectomy | 1 |
Active & Upcoming Studies in Urbana (2026)
Recruiting trials in Urbana grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (110 active studies)
- Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations · Phase 3 · SWOG Cancer Research Network
- A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202) · Phase 3 · Bristol-Myers Squibb
Neurology & pain (6 active studies)
- Optimal Targeted High-definition Transcranial Direct Current Stimulation for Reducing Post-stroke Upper Limb Motor Impairments · Carle Foundation Hospital
- Pain Management for In-Office Gynecologic Procedures Using a Risk-Stratification Pain Calculator · Carle Foundation Hospital
Mental health & behavior (2 active studies)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
- Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program · Phase 3 · Alliance for Clinical Trials in Oncology
Diabetes & metabolic (2 active studies)
- Exercise and Protein Efficiency in T2D · University of Illinois at Urbana-Champaign
- Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL) · University of Illinois at Urbana-Champaign
Cardiovascular (2 active studies)
- Distal Evaluation of Functional Performance with Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting · Philips Clinical & Medical Affairs Global
- The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR · Cardiac Dimensions, Inc.
Pediatric (1 active study)
- Plants Optimizing Development Study (PODS) · University of Illinois at Urbana-Champaign
Common conditions studied in Urbana
- Breast Cancer (8 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Stage IV Lung Cancer AJCC v8 (8 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Malignant Solid Neoplasm (7 active studies). Recruiting Malignant Solid Neoplasm studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Stage IVB Prostate Cancer AJCC v8 (5 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Anatomic Stage IV Breast Cancer AJCC v8 (4 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
Leading research sponsors in Urbana
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- NRG Oncology
- Alliance for Clinical Trials in Oncology
- University of Illinois at Urbana-Champaign
Local regulations and guidelines
Clinical trials in Illinois are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Illinois studies must also comply with the Illinois Personal Information Protection Act (PIPA) and Biometric Information Privacy Act (BIPA) where applicable.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Urbana. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Urbana
Hipa.ai aggregates every recruiting study in Urbana from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Urbana?
There are approximately 152 recruiting clinical trials in Urbana, Illinois listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Urbana pay participants?
Most recruiting trials in Urbana compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Urbana?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Urbana?
The most common conditions under active study in Urbana include Breast Cancer (8), Stage IV Lung Cancer AJCC v8 (8), Malignant Solid Neoplasm (7), Stage IVB Prostate Cancer AJCC v8 (5), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Urbana?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Urbana on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Urbana?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Urbana?
Recruiting research sites in Urbana include Carle Cancer Center, The Carle Foundation Hospital, Carle Foundation Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Urbana right now?
The largest active categories in Urbana are Cancer & tumors (110), Neurology & pain (6), Mental health & behavior (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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