Paid Clinical Trials in South Carolina

South Carolina has 1,276 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,276 clinical trials

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Use of a Cloud-connected Remote Blood Pressure Monitoring Program During the Postpartum Period for Hypertensive Women

for Hypertensive Disorder

1 location in Columbia

Sponsor: University of South Carolina

Sex: Female·Age: 18 - 54

Code: NCT06096701·Recruiting

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Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis (IPF)

12 locations incl. Birmingham

Sponsor: InSilico Medicine Hong Kong Limited

Sex: All·Age: 40+

Code: NCT05975983·Phase 2·Recruiting

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A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer

for Small Cell Lung Cancer

30 locations incl. Daphne

Sponsor: Puma Biotechnology, Inc.

Sex: All·Age: 18+

Code: NCT06095505·Phase 2·Recruiting

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MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

for Multiple Myeloma

Drug: Elranatamab

97 locations incl. Mobile

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06152575·Phase 3·Recruiting

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A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

for Antineutrophil Cytoplasmic Antibody-associated Vasculitis

Drug: Avacopan

60 locations incl. Anchorage

Sponsor: Amgen

Sex: All·Age: 18 - 100

Code: NCT06072482·Phase 4·Recruiting

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A Study of AK117 in Combination With Azacitidine in Patients With Myelodysplastic Syndromes

for Higher-risk Myelodysplastic Syndromes

14 locations incl. Los Angeles

Sponsor: Akeso

Sex: All·Age: 18+

Code: NCT06196203·Phase 2·Recruiting

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Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma

for Follicular Lymphoma (FL)

Drug: Epcoritamab

58 locations incl. Fresno

Sponsor: Genmab

Sex: All·Age: 18+

Code: NCT06191744·Phase 3·Recruiting

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Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

for Muscle Invasive Bladder Urothelial Carcinoma

490 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05987241·Phase 2, Phase 3·Recruiting

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RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS

for Healthy

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05977439·Recruiting

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taVNS-Paired Breastfeeding to Improve Breastfeeding at Discharge

for Premature Birth

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 35 Weeks+·Accepts healthy volunteers

Code: NCT06417385·Recruiting

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Mobile Health for Adherence in Breast Cancer Patients

for Anatomic Stage IV Breast Cancer AJCC v8

499 locations incl. Fairbanks

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06112613·Recruiting

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A Study of ZL-1310 in Subjects With Small Cell Lung Cancer

for SCLC

Drug: ZL-1310

11 locations incl. Duarte

Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All·Age: 18+

Code: NCT06179069·Phase 1·Recruiting

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A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

for Multiple Myeloma

Drug: Talquetamab

49 locations incl. Clovis

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06208150·Phase 3·Recruiting

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A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

for Heart Failure

Drug: Finerenone

77 locations incl. Birmingham

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06008197·Phase 3·Recruiting

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A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

for Metastatic Head-and-neck Squamous-cell Carcinoma

28 locations incl. Gilbert

Sponsor: AVEO Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06064877·Phase 3·Recruiting

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LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF

for Pulmonary Hypertension

41 locations incl. Tucson

Sponsor: Tenax Therapeutics, Inc.

Sex: All·Age: 18 - 85

Code: NCT05983250·Phase 3·Recruiting

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Investigation of Skin Pigmentation Effect on Performance of Masimo Pulse Oximetry (INSPIRE)

for Hypoxemia

1 location in Charleston

Sponsor: Masimo Corporation

Sex: All·Age: 18 - 89

Code: NCT06432881·Recruiting

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SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

for Chronic Kidney Diseases

28 locations incl. Bullhead City

Sponsor: VenoStent

Sex: All·Age: 18+

Code: NCT06001827·Recruiting

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Optimal Digital Weight Loss Treatment for Rural Individuals

for Overweight and Obesity

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06105957·Recruiting

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Novel Cellular Therapy for the Treatment of Pain Associated With Chronic Pancreatitis

for Chronic Pancreatitis

1 location in Charleston

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT05925036·Phase 1·Recruiting

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A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)

for Essential Thrombocythemia

16 locations incl. Glendale

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06079879·Phase 3·Recruiting

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Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

for Prostate Cancer Metastatic

44 locations incl. Orange

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: All ages

Code: NCT06136624·Phase 3·Recruiting

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BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

for Hypertension

70 locations incl. Scottsdale

Sponsor: Orchestra BioMed, Inc

Sex: All·Age: 18+

Code: NCT06059638·Recruiting

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Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

for Prostate Cancer

27 locations incl. Birmingham

Sponsor: Clarity Pharmaceuticals Ltd

Sex: Male·Age: 18+

Code: NCT06056830·Phase 3·Recruiting

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A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: LY3537982

91 locations incl. Huntsville

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06119581·Phase 3·Recruiting

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Cord Clamping Among Neonates With Congenital Heart Disease

for Congenital Heart Disease (CHD)

18 locations incl. Birmingham

Sponsor: Carl Backes, MD

Sex: All·Age: 37 Weeks - 42 Weeks

Code: NCT06153459·Recruiting

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A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

for Metastatic Castration-resistant Prostate Cancer (mCRPC)

62 locations incl. Tucson

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06136650·Phase 3·Recruiting

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RESEARCH EVALUATING VAGAL EXCITATION AND ANATOMICAL LINKS

for Epilepsy

5 locations incl. Stanford

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06143293·Recruiting

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Vitamin D for Prostate Endocrine Therapy

for Stage I Prostate Cancer AJCC v8

51 locations incl. Newark

Sponsor: University of Rochester

Sex: Male·Age: 50+

Code: NCT05838716·Phase 3·Recruiting

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Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

for Prostate Adenocarcinoma

388 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Male·Age: 18+

Code: NCT05946213·Phase 3·Recruiting

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MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

for Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

38 locations incl. Tucson

Sponsor: Intellia Therapeutics

Sex: All·Age: 18 - 90

Code: NCT06128629·Phase 3·Recruiting

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A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)

for Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer

Drug: Giredestrant

61 locations incl. Daphne

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06065748·Phase 3·Recruiting

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A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

23 locations incl. Tucson

Sponsor: Eikon Therapeutics

Sex: All·Age: 18 - 89

Code: NCT06253130·Phase 1, Phase 2·Recruiting

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Zenith® Fenestrated+ Clinical Study

for Aortic Aneurysm, Abdominal

32 locations incl. Birmingham

Sponsor: Cook Research Incorporated

Sex: All·Age: 18+

Code: NCT04875429·Recruiting

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ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation vs Control in Redo Ablation Patients

for Paroxysmal Atrial Fibrillation

8 locations incl. Jonesboro

Sponsor: Vivek Reddy

Sex: All·Age: 18+

Code: NCT05988411·Recruiting

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A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma

for Choroidal Melanoma

36 locations incl. Birmingham

Sponsor: Aura Biosciences

Sex: All·Age: 18+

Code: NCT06007690·Phase 3·Recruiting

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A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

for Non-small Cell Lung Cancer

Drug: Intismeran autogene

68 locations incl. Anchorage

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06077760·Phase 3·Recruiting

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LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

for Advanced Colorectal Carcinoma

225 locations incl. Fort Smith

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT06073431·Recruiting

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Beneficial or Fostering Future Struggles (B.F.F.s)? Characterizing the Role of Friends in the Development of 13- to 17-Year-Old Adolescents

for Child Maltreatment

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 13 - 17·Accepts healthy volunteers

Code: NCT05893459·Recruiting

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A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

for NASH With Fibrosis

Drug: Efruxifermin

205 locations incl. Birmingham

Sponsor: Akero Therapeutics, Inc

Sex: All·Age: 18 - 80

Code: NCT06215716·Phase 3·Recruiting

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