Paid Clinical Trials in South Carolina

South Carolina has 1,276 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,276 clinical trials

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Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors

for Advanced Solid Tumor

7 locations incl. Louisville

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06750185·Phase 1·Recruiting

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A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

for Sickle Cell Disease

Drug: Etavopivat

39 locations incl. Birmingham

Sponsor: Novo Nordisk A/S

Sex: All·Age: 2+

Code: NCT06609226·Phase 3·Recruiting

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A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)

for Type 2 Diabetes

Drug: Dulaglutide

41 locations incl. Tucson

Sponsor: Eli Lilly and Company

Sex: All·Age: 10 - 17

Code: NCT06739122·Phase 3·Recruiting

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A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age

for Chickenpox

60 locations incl. Mobile

Sponsor: GlaxoSmithKline

Sex: All·Age: 12 Months - 15 Months·Accepts healthy volunteers

Code: NCT06740630·Phase 3·Recruiting

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UC-MSC Cell Therapy Study for Systemic Lupus Erythematosus (SLE) Patients

for SLE

1 location in Charleston

Sponsor: LiveKidney.Bio

Sex: All·Age: 18 - 75

Code: NCT06737380·Phase 1·Recruiting

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A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

for Crohn's Disease

Drug: Upadacitinib

19 locations incl. La Jolla

Sponsor: Takeda

Sex: All·Age: 18 - 65

Code: NCT06227910·Phase 3·Recruiting

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Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma

for Cutaneous Squamous Cell Carcinoma (CSCC)

Drug: Cemiplimab

45 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06585410·Phase 3·Recruiting

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Effectiveness and Safety of the RIGHTEST Continuous Glucose Monitoring System for Blood Glucose Management in Persons With Diabetes Mellitus

for Diabetes Mellitus

13 locations incl. Guntersville

Sponsor: Bionime Corporation

Sex: All·Age: 18+

Code: NCT04838392·Not Yet Recruiting

A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

for Narcolepsy Type 1

Drug: ORX750

29 locations incl. Auburn

Sponsor: Centessa Pharmaceuticals (UK) Limited

Sex: All·Age: 18 - 65

Code: NCT06752668·Phase 2·Recruiting

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Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

for Heart Failure

88 locations incl. Alexander City

Sponsor: Cytokinetics

Sex: All·Age: 18 - 85

Code: NCT06736574·Phase 3·Recruiting

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A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

for Graves' Disease

Drug: IMVT-1402

64 locations incl. Phoenix

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 75

Code: NCT06727604·Phase 2·Recruiting

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Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation

for Locally Advanced, Unresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Drug: Durvalumab

8 locations incl. Los Alamitos

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT06501625·Phase 1, Phase 2·Recruiting

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A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for Carcinoma, Non-Small-Cell Lung

Drug: Amivantamab

150 locations incl. Daphne

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06667076·Phase 2·Recruiting

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ViewFlex X ICE First-in-Human Study

for Cardiac Arrhythmias

8 locations incl. Jonesboro

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT06772493·Recruiting

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Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

for Heart Failure

57 locations incl. Phoenix

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT06526195·Recruiting

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Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

for Anatomic Stage IV Breast Cancer AJCC v8

256 locations incl. Tucson

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06500455·Phase 3·Recruiting

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A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma

for Asthma

85 locations incl. Phoenix

Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All·Age: 12+

Code: NCT06664619·Phase 3·Recruiting

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Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

for Cystic Fibrosis

13 locations incl. Tucson

Sponsor: Arcturus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06747858·Phase 2·Recruiting

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A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

for Moderately to Severely Active Ulcerative Colitis

Drug: Afimkibart

71 locations incl. Dothan

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06588855·Phase 3·Recruiting

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Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

for Resectable Lung Non-Small Cell Carcinoma

378 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06632327·Phase 3·Recruiting

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A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Crohn's Disease.

for Crohn's Disease

19 locations incl. Sun City

Sponsor: Sanofi

Sex: All·Age: 18 - 75

Code: NCT06637631·Phase 2·Recruiting

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A Study to Evaluate the Efficacy and Safety of Autogene Cevumeran With Nivolumab Versus Nivolumab Alone in Participants With High-risk Muscle-invasive Urothelial Carcinoma (MIUC)

for Muscle-invasive Urothelial Carcinoma

Drug: Nivolumab

26 locations incl. Springdale

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06534983·Phase 2·Recruiting

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Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder (ASD) in Pediatric Patients

for Irritability Associated With Autism Spectrum Disorder

39 locations incl. Little Rock

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 5 - 17

Code: NCT06706674·Phase 3·Recruiting

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HVIP Outcomes and Stakeholder Insights

for Firearm Injury

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 16+·Accepts healthy volunteers

Code: NCT06582953·Recruiting

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Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor

for Patients With Non-Small Cell Lung Cancer

Drug: OSE2101

79 locations incl. Beverly Hills

Sponsor: OSE Immunotherapeutics

Sex: All·Age: 18+

Code: NCT06472245·Phase 3·Recruiting

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Efficacy of Intramuscular Steroid Injection for Chronic Cough.

for Chronic Cough (CC)

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06634823·EARLY_Phase 1·Recruiting

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A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)

for Coronavirus Disease (COVID-19)

71 locations incl. Cullman

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06667700·Phase 3·Recruiting

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Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

for Cystic Fibrosis

31 locations incl. Birmingham

Sponsor: University of Washington, the Collaborative Health Studies Coordinating Center

Sex: All·Age: 3 - 18

Code: NCT06654752·Recruiting

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The Immediate and 24-hour Effects of Body Tempering Versus Foam Rolling on Lower Extremity Muscular Power During the Vertical Jump and Standing Long Jump Tests

for Lower Extremity Muscular Power Performance Output

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 18 - 39·Accepts healthy volunteers

Code: NCT06646926·Not Yet Recruiting

Measuring Outcomes of LASIK and EVO-ICL in Matched Populations

for Myopia

5 locations incl. Omaha

Sponsor: Vance Thompson Vision

Sex: All·Age: 21 - 45

Code: NCT06700460·Recruiting

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Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer

for Prostate Cancer

7 locations incl. San Francisco

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT06613100·Phase 1·Recruiting

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A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

for Eosinophilic Esophagitis (EoE)

54 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 1+

Code: NCT06693531·Recruiting

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A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular Degeneration

for Neovascular Age-related Macular Degeneration

18 locations incl. Phoenix

Sponsor: Sanofi

Sex: All·Age: 50 - 90

Code: NCT06660667·Phase 1, Phase 2·Recruiting

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Accelerated TMS for Freezing of Gait in Parkinson's Disease

for Parkinson&#39

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 50 - 80

Code: NCT06982638·Recruiting

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Understanding and Enhancing Health-Related Social Needs (HRSN) Screening Among Community Oncology Practices

for Cancer

33 locations incl. Newark

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06412029·Enrolling By Invitation

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for Lung Non-Small Cell Carcinoma

248 locations incl. Jonesboro

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06116682·Phase 2·Recruiting

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Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

for Chronic Granulomatous Disease (CGD)

50 locations incl. Montgomery

Sponsor: Ensoma

Sex: All·Age: All ages

Code: NCT06605378·Recruiting

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Resilience Through Interventions for Successful Early Outcomes

for Parenting Intervention

1 location in Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18+

Code: NCT06669624·Recruiting

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Epilepsy Journey-An Executive Functioning Intervention for Teens With Epilepsy

for Epilepsy in Children

3 locations incl. Orange

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 13 - 17

Code: NCT06608966·Recruiting

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Imaging Biomarkers of FOG Response to DBS

for Freezing of Gait Symptoms in Parkinson&#39

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 40+

Code: NCT06951906·Phase 4·Recruiting

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