Behavioral health Clinical Trials in San Francisco, CA

As of June 2026, 67 paid clinical trials are recruiting for Behavioral health in San Francisco, California. Behavioral health trials span mental-health pharmacotherapy and addiction treatment — testing new agents and therapies for depression, anxiety, opioid use disorder, alcohol use, and tobacco cessation. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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67 clinical trials for Behavioral health

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CONNECTing to LungCare

for Smoking Cessation

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06213532·Recruiting

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Studying Patterns in Patient Engagement Among Treatment Resistant Depression Patients

for Treatment Resistant Depression

1 location in San Francisco

Sponsor: Power Life Sciences Inc.

Sex: All·Age: 18+

Code: NCT06101914·Not Yet Recruiting

Precision Care for Major Depressive Disorder

for Major Depressive Disorder

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06580041·Phase 4·Enrolling By Invitation

Efficacy and Safety of a Proprietary Blend of Ashwagandha Root Extract (Aqueous) in Adult Men and Women With High Stress and Anxiety: A Randomized, Double-blind, Three-arm, Parallel, Placebo-controlled Study

for Stress

1 location in San Francisco

Sponsor: SF Research Institute, Inc.

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06714942·Recruiting

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Hybrid Effectiveness-Implementation Trial of a School Clinician Training and Psychosocial ADHD/ODD Intervention Program Adapted for Schools Across Mexico

for ADHD

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 5+

Code: NCT06457256·Enrolling By Invitation

Assessment of Schizophrenia Patients' Clinical Study Experiences

for Schizophrenia

1 location in San Francisco

Sponsor: Power Life Sciences Inc.

Sex: All·Age: 18+

Code: NCT05948111·Not Yet Recruiting

Psilocybin Therapy for Depression in Parkinson's Disease

for Parkinson Disease

1 location in San Francisco

Sponsor: Joshua Woolley, MD, PhD

Sex: All·Age: 40 - 80

Code: NCT06455293·Phase 2·Recruiting

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A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations

for PTSD

2 locations incl. Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT06367764·Recruiting

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Exploring Clinical Study Experiences of People With Depression

for Depression

1 location in San Francisco

Sponsor: Power Life Sciences Inc.

Sex: All·Age: 18+

Code: NCT05937932·Not Yet Recruiting

Discovering Factors in the Clinical Study Journey of Patients With OCD

for OCD

1 location in San Francisco

Sponsor: Power Life Sciences Inc.

Sex: All·Age: 18+

Code: NCT05881356·Recruiting

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A Close Examination of Patient Experiences in Bipolar Disorder Clinical Trials

for Bipolar Disorder

1 location in San Francisco

Sponsor: Power Life Sciences Inc.

Sex: All·Age: 18+

Code: NCT05891639·Not Yet Recruiting

Building Resilience for Surgical Recovery

for Psychosocial Functioning

1 location in San Francisco

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 65+

Code: NCT06174701·Recruiting

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Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment.

for Opioid Use Disorder

6 locations incl. Oakland

Sponsor: Yale University

Sex: All·Age: 18 - 99

Code: NCT06323824·Phase 4·Recruiting

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Cultural Adaptation of Drug Treatment for DJJ Youth

for Substance Use

2 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 13 - 17·Accepts healthy volunteers

Code: NCT06003725·Recruiting

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Supporting Peer Interactions to Expand Access to Digital Cognitive Behavioral Therapy for Spanish-speaking Patients

for Depression, Anxiety

11 locations incl. Payson

Sponsor: University of California, Irvine

Sex: All·Age: 18+

Code: NCT05746767·Enrolling By Invitation

ChangeGradients: Promoting Adolescent Health Behavior Change

for Alcohol Drinking

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 15 - 17·Accepts healthy volunteers

Code: NCT04110756·Recruiting

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Brief Behavioral Treatment for Insomnia in Veterans With Posttraumatic Stress Disorder

for Posttraumatic Stress Disorder

1 location in San Francisco

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT05780177·Recruiting

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Phase IIa Trial of a Selective Glucocorticoid Receptor Antagonist in the Treatment of Veterans With Posttraumatic Stress Disorder (PTSD) (Seven Study)

for PTSD

2 locations incl. Tuscaloosa

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 69

Code: NCT04452500·Phase 2·Recruiting

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Using Electrophysiology to Index Non-invasive Brain Stimulation Effects on Reward System Functioning in Depression

for Major Depressive Disorder

1 location in San Francisco

Sponsor: San Francisco Veterans Affairs Medical Center

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05194098·Recruiting

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Cortical Stimulation to Treat Obsessive Compulsive Disorder

for Obsessive-Compulsive Disorder

1 location in San Francisco

Sponsor: Andrew Moses Lee, MD, PhD

Sex: All·Age: 22 - 75

Code: NCT04958096·Recruiting

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Reward Processing and Depressive Subtypes: Identifying Neural Biotypes

for Depression

1 location in San Francisco

Sponsor: San Francisco Veterans Affairs Medical Center

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06080646·Recruiting

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Lung Macrophage Populations and Functions in Chronic Obstructive Pulmonary Disease (COPD)-Susceptible Smokers

for Copd

3 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT04722835·Recruiting

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Medial-prefrontal Enhancement During Schizophrenia Systems Imaging

for Schizophrenia

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT04807530·Recruiting

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A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder

for Opioid Use Disorder

25 locations incl. Tuscaloosa

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT04375033·Phase 4·Recruiting

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Closed-Loop Deep Brain Stimulation for Major Depression

for Major Depressive Disorder

1 location in San Francisco

Sponsor: Andrew Krystal

Sex: All·Age: 22 - 70

Code: NCT04004169·Recruiting

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Near Infrared Spectroscopy (NIRS) for Assessment of Depression

for Major Depressive Disorder

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04061148·Recruiting

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Spatiotemporal Dynamics of the Human Emotion Network

for Epilepsy

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 50

Code: NCT05152992·Enrolling By Invitation

Conditions in Behavioral health (San Francisco, CA)

Depression· 20 Tobacco / nicotine use· 12 Anxiety· 7 PTSD (post-traumatic stress disorder)· 7 Opioid use disorder· 6 Substance use disorder· 5 Schizophrenia· 4 Alcohol use disorder· 4 Obsessive-compulsive disorder (OCD)· 3 Bipolar disorder· 1 ADHD· 1 Cannabis use / cannabis use disorder· 1