STELLA-FTD: Examination of a Behavior Change Intervention for FTD Family Care Partnersfor Frontotemporal Dementia1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 18 - 100·Accepts healthy volunteersCode: NCT06613204·RecruitingApply to this trial
Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms With Surpass Elite With GUARDian Flow Diverter (GUARD)for Aneurysm10 locations incl. TucsonSponsor: Stryker NeurovascularSex: All·Age: 18 - 80Code: NCT06872684·RecruitingApply to this trial
Prevention of Ototoxicity in NTM Patients Treated With IV Amikacinfor Ototoxicity, Drug-Induced7 locations incl. San FranciscoSponsor: Kevin WinthropSex: All·Age: 18 - 80Code: NCT05730283·Phase 2·RecruitingApply to this trial
Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)for B-cell Acute Lymphoblastic Leukemia9 locations incl. DuarteSponsor: Vironexis Biotherapeutics Inc.Sex: All·Age: 13 - 90Code: NCT06533579·Phase 1, Phase 2·RecruitingApply to this trial
Brief Sleep Intervention for Bedtime Resistancefor Child Sleep1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 18+Code: NCT06970392·RecruitingApply to this trial
CGM for the Early Detection and Management of Hyperglycemia in Pregnancyfor Gestational Diabetes Mellitus in Pregnancy8 locations incl. BirminghamSponsor: Jaeb Center for Health ResearchSex: Female·Age: 18+·Accepts healthy volunteersCode: NCT06957028·RecruitingApply to this trial
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variantfor AmyloidosisDrug: Acoramidis39 locations incl. La JollaSponsor: Eidos Therapeutics, a BridgeBio companySex: All·Age: 18 - 75Code: NCT06563895·Phase 3·RecruitingApply to this trial
The Development of PATH, a Program to Support NICU Parent Mental Health Through the Transition From Hospital to Homefor Perinatal Mental Health2 locations incl. AuroraSponsor: University of Colorado, DenverSex: All·Age: All agesCode: NCT06467916·RecruitingApply to this trial
EXtubation Related Complications - the EXTUBE Study (EXTUBE)for Extubation6 locations incl. TucsonSponsor: University Health Network, TorontoSex: All·Age: 18+Code: NCT06442930·RecruitingApply to this trial
A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)for Graft-versus-host Disease (GVHD)Drug: Ruxolitinib30 locations incl. Palo AltoSponsor: Incyte CorporationSex: All·Age: 18+Code: NCT06615050·Phase 3·RecruitingApply to this trial
A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)for Gastrointestinal Stromal Tumor (GIST)32 locations incl. BirminghamSponsor: Kura Oncology, Inc.Sex: All·Age: 18+Code: NCT06655246·Phase 1·RecruitingApply to this trial
A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopeniafor Immune Thrombocytopenic Purpura (ITP)18 locations incl. Los AngelesSponsor: TakedaSex: All·Age: 18+Code: NCT06722235·Phase 3·RecruitingApply to this trial
OTAGO Exercise Program and Motivational Interviewingfor Fall Risk Factors1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 60 - 120Code: NCT06931067·RecruitingApply to this trial
A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1)for Stargardt Disease5 locations incl. AuroraSponsor: Splice BioSex: All·Age: 12 - 65Code: NCT06942572·Phase 1, Phase 2·RecruitingApply to this trial
A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kitfor Gastrointestinal Stromal Tumors5 locations incl. Ann ArborSponsor: Novelty Nobility, Inc.Sex: All·Age: 18+Code: NCT06805825·Phase 1·RecruitingApply to this trial
DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)for Pulmonary Hypertension Due to Lung Diseases and Hypoxia66 locations incl. BirminghamSponsor: United TherapeuticsSex: All·Age: 18+Code: NCT06388421·RecruitingApply to this trial
eDoula Feasibility and Acceptabilityfor Pregnancy Related1 location in PortlandSponsor: Oregon Health and Science UniversitySex: Female·Age: 18 - 50Code: NCT06785467·RecruitingApply to this trial
Mediators and Moderators of Auditory Trainingfor Hearing Handicap3 locations incl. RiversideSponsor: Northeastern UniversitySex: All·Age: 18 - 85·Accepts healthy volunteersCode: NCT06812273·RecruitingApply to this trial
Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinomafor Cutaneous Squamous Cell Carcinoma (CSCC)Drug: Cemiplimab45 locations incl. PhoenixSponsor: Regeneron PharmaceuticalsSex: All·Age: 18+Code: NCT06585410·Phase 3·RecruitingApply to this trial
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failurefor Heart Failure57 locations incl. PhoenixSponsor: Abbott Medical DevicesSex: All·Age: 18+Code: NCT06526195·RecruitingApply to this trial
Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohortsfor Pancreatic Carcinoma9 locations incl. ScottsdaleSponsor: Mayo ClinicSex: All·Age: 18+Code: NCT06271291·RecruitingApply to this trial
Streamlined Treatment of Pulmonary Exacerbations in Pediatricsfor Cystic Fibrosis31 locations incl. BirminghamSponsor: University of Washington, the Collaborative Health Studies Coordinating CenterSex: All·Age: 3 - 18Code: NCT06654752·RecruitingApply to this trial
Accelerated Flap Coverage in Severe Lower Extremity Traumafor Open Tibia Fracture7 locations incl. SacramentoSponsor: Johns Hopkins UniversitySex: All·Age: 18+Code: NCT06293469·RecruitingApply to this trial
J-Valve Transfemoral Pivotal Studyfor Aortic Valve Regurgitation34 locations incl. ScottsdaleSponsor: JC Medical, Inc., an affiliate of Edwards Lifesciences LLCSex: All·Age: 18+Code: NCT06455787·RecruitingApply to this trial
A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemiafor Leukemia, Juvenile MyelomonocyticDrug: Trametinib19 locations incl. PhoenixSponsor: Therapeutic Advances in Childhood Leukemia ConsortiumSex: All·Age: 1 Month - 21Code: NCT05849662·Phase 1, Phase 2·RecruitingApply to this trial
Safety and Effectiveness of Mechanical Thrombectomy Using the Anaconda ANA Funnel Catheterfor Acute Ischemic Stroke From Large Vessel Occlusion11 locations incl. JacksonvilleSponsor: Anaconda Biomed S.L.Sex: All·Age: 22 - 85Code: NCT06370182·RecruitingApply to this trial
AltaValve Pivotal Trialfor Mitral Regurgitation20 locations incl. PhoenixSponsor: 4C Medical Technologies, Inc.Sex: All·Age: 18+Code: NCT06465745·RecruitingApply to this trial
A Study of Bleeding and Treatment in Participants With Von Willebrand Diseasefor Von Willebrand Disease (VWD)13 locations incl. PhoenixSponsor: Hemab ApSSex: All·Age: 16+Code: NCT06610201·RecruitingApply to this trial
Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)for Antiphospholipid Syndrome (APS)11 locations incl. OrangeSponsor: Chugai PharmaceuticalSex: All·Age: 18 - 85Code: NCT06371417·Phase 1·RecruitingApply to this trial
Rural Community Peer Partnerships for Improving Methamphetamine-Associated Heart Failure Screening and Engagementfor Methamphetamine Use1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 18+Code: NCT06461962·RecruitingApply to this trial
A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasmsfor Myeloproliferative Neoplasms13 locations incl. BirminghamSponsor: Incyte CorporationSex: All·Age: 18+Code: NCT06313593·Phase 1·RecruitingApply to this trial
Bomedemstat vs Hydroxyurea for Essential Thrombocythemia (MK-3543-007)for Essential Thrombocythemia22 locations incl. GlendaleSponsor: Merck Sharp & Dohme LLCSex: All·Age: 18+Code: NCT06456346·Phase 3·RecruitingApply to this trial
The Influence of Sleep on Cardiovascular Outcomesfor Circadian Rhythm1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 18 - 50·Accepts healthy volunteersCode: NCT06535178·RecruitingApply to this trial
Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndromefor Acute Respiratory Distress Syndrome33 locations incl. TucsonSponsor: Beth Israel Deaconess Medical CenterSex: All·Age: 18+Code: NCT06066502·Phase 3·RecruitingApply to this trial
Wearable Technology to Characterize and Treat mTBI Subtypes: Biofeedback-Based Precision Rehabilitationfor Mild Traumatic Brain Injury, Concussion3 locations incl. PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 18 - 60Code: NCT06381674·RecruitingApply to this trial
A Study of Tinengotinib (TT-00420) in Combination With Standard Treatments in People With Prostate Cancerfor Prostate Cancer12 locations incl. New HavenSponsor: Memorial Sloan Kettering Cancer CenterSex: Male·Age: 18+Code: NCT06457919·Phase 1, Phase 2·RecruitingApply to this trial
Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemiafor AML With Gene Mutations12 locations incl. Los AngelesSponsor: Lomond Therapeutics Holdings, Inc.Sex: All·Age: 18+Code: NCT06366789·Phase 1·RecruitingApply to this trial
A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).for PediatricDrug: Aficamten26 locations incl. PhoenixSponsor: CytokineticsSex: All·Age: 12 - 17Code: NCT06412666·Phase 2, Phase 3·RecruitingApply to this trial
IMPRoving Outcomes in Vascular DisEase - Aortic Dissectionfor Type B Aortic Dissection61 locations incl. BirminghamSponsor: Duke UniversitySex: All·Age: 21+Code: NCT06087029·RecruitingApply to this trial
The HYALEX Pivotal Studyfor Damaged Chondral or Osteochondral Area4 locations incl. La MesaSponsor: Hyalex Orthopaedics, Inc.Sex: All·Age: 22 - 70Code: NCT06368700·RecruitingApply to this trial