Clinical Trials at University of Pittsburgh Medical Center

As of June 2026, 150 paid clinical trials are recruiting at University of Pittsburgh Medical Center, located at 200 LOTHROP ST, 933 W MONTEFIORE, PITTSBURGH, PA 15213-2536, phone (412) 692-4834 in Pittsburgh, Pennsylvania. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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150 clinical trials at University of Pittsburgh Medical Center

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KRT-232 and TKI Study in Chronic Myeloid Leukemia

for Chronic Myeloid Leukemia

5 locations incl. Birmingham

Sponsor: Kartos Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT04835584·Phase 1, Phase 2·Recruiting

Apply to this trial

Evaluation of a Mixed Meal Test for Diagnosis and Characterization and Type 3c Diabetes Mellitus Secondary to Pancreatic Cancer and Chronic Pancreatitis (DETECT)

for Pancreatic Cancer

10 locations incl. Los Angeles

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 30 - 84

Code: NCT03460769·Recruiting

Apply to this trial

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

for Advanced Solid Tumor

32 locations incl. Irvine

Sponsor: PMV Pharmaceuticals, Inc

Sex: All·Age: 12+

Code: NCT04585750·Phase 1, Phase 2·Recruiting

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Evaluating Treatment of ADHD in Children with Down Syndrome

for Down Syndrome

4 locations incl. Sacramento

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 6 - 17·Accepts healthy volunteers

Code: NCT04219280·Phase 4·Recruiting

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A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

for Solid Tumor

6 locations incl. Gilbert

Sponsor: ImmVira Pharma Co. Ltd

Sex: All·Age: 18+

Code: NCT04370587·Phase 1, Phase 2·Recruiting

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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

102 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting

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A Study to Test Different Doses of Obrixtamig in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3

for Small Cell Lung Carcinoma and Other Neuroendocrine Neoplasms Expressing DLL3

Drug: Obrixtamig

4 locations incl. Atlanta

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT04429087·Phase 1·Recruiting

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TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers

for Cancer

41 locations incl. Tucson

Sponsor: Tizona Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT04485013·Phase 1·Recruiting

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Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Prostate Cancer

25 locations incl. Duarte

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT04221542·Phase 1·Recruiting

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Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow

for Neuropathy Ulnar

10 locations incl. Atlanta

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT04254185·Recruiting

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Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0

for Cervical Deformity

16 locations incl. La Jolla

Sponsor: International Spine Study Group Foundation

Sex: All·Age: 18+

Code: NCT04194996·Recruiting

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ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

for Refractory Cancer

Drug: Nivolumab

13 locations incl. Stanford

Sponsor: Immatics US, Inc.

Sex: All·Age: 18+

Code: NCT03686124·Phase 1, Phase 2·Recruiting

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Metformin for Pulmonary Hypertension HFpEF

for Pulmonary Hypertension

2 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT03629340·Phase 2·Recruiting

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Molecular and Cellular Characterization of Skull Base Tumors

for Skull Base Neoplasm

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: All ages

Code: NCT03759717·Recruiting

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Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

for Spinal Muscular Atrophy (SMA)

50 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: All ages

Code: NCT04174157·Recruiting

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Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis

for Systemic Sclerosis

3 locations incl. Pittsburgh

Sponsor: Paul Szabolcs

Sex: All·Age: 8 - 60

Code: NCT03630211·Phase 2·Recruiting

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A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

for Metastatic Breast Cancer

16 locations incl. Duarte

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT03424005·Phase 1, Phase 2·Recruiting

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Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC

for Locally Advanced Pancreatic Cancer

36 locations incl. Loma Linda

Sponsor: RenovoRx

Sex: All·Age: 18+

Code: NCT03257033·Phase 3·Recruiting

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The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

for Functional Mitral Regurgitation

75 locations incl. Gilbert

Sponsor: Cardiac Dimensions, Inc.

Sex: All·Age: 18+

Code: NCT03142152·Recruiting

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Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

for Heart Failure With Preserved Ejection Fraction

38 locations incl. Alexander City

Sponsor: Uppsala University

Sex: All·Age: 50 - 99

Code: NCT02901184·Phase 3·Recruiting

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QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing

for Chronic Pancreatitis

2 locations incl. Baltimore

Sponsor: Anna Evans Phillips

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03434392·Recruiting

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Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS)

for Alveolar Soft Part Sarcoma

17 locations incl. Phoenix

Sponsor: Advenchen Laboratories, LLC

Sex: All·Age: 18+

Code: NCT03016819·Phase 3·Recruiting

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INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)

for Glioblastoma

12 locations incl. Birmingham

Sponsor: Patrick Wen, MD

Sex: All·Age: 18+

Code: NCT02977780·Phase 2·Recruiting

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The Myelin Disorders Biorepository Project

for Leukodystrophy

23 locations incl. Los Angeles

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT03047369·Recruiting

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Pulmonary Hypertension Association Registry

for Pulmonary Arterial Hypertension

52 locations incl. Phoenix

Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All·Age: 0+

Code: NCT04071327·Recruiting

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International Rare Histiocytic Disorders Registry (IRHDR)

for Rare Histiocytic Disorders (RHDs)

6 locations incl. Birmingham

Sponsor: The Hospital for Sick Children

Sex: All·Age: All ages

Code: NCT02285582·Recruiting

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

142 locations incl. Birmingham

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting

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Inflammatory Bowel Disease (IBD) Research Registry

for Inflamatory Bowel Disease (Crohn's and Ulcerative Colitis)

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04243525·Recruiting

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Collection of Tissue Samples for Cancer Research

for Neoplasms

16 locations incl. Sacramento

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 Months+

Code: NCT00900198·Recruiting

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Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research

for Cutaneous T-cell Lymphoma

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT00177268·Recruiting

Apply to this trial