Paid Clinical Trials in Philadelphia, PA

As of June 2026, 2,103 paid clinical trials are recruiting in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 18, 2026.

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2,103 clinical trials

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The Effects of an Acute Dose of a Betalain-rich Concentrate on Repeated-sprint Cycling Performance and Recovery.

for Nutraceuticals

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT06274385·Recruiting

Apply to this trial

Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant Candidates

for Liver Transplant

18 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06075745·Phase 2·Recruiting

Apply to this trial

AETOS Shoulder System

for Shoulder Osteoarthritis

5 locations incl. San Francisco

Sponsor: Smith & Nephew, Inc.

Sex: All·Age: 18+

Code: NCT06319911·Recruiting

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iCare4Me Transitions

for Caregiver Stress

3 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06167746·Phase 3·Recruiting

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An Open-label Extension Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis

for Pulmonary Sarcoidosis

5 locations incl. Denver

Sponsor: Xentria, Inc.

Sex: All·Age: 18 - 80

Code: NCT06169397·Phase 2·Enrolling By Invitation

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor

for Dermatitis Atopic

Drug: Amlitelimab

42 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 12+

Code: NCT06241118·Phase 3·Recruiting

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A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

for Solid Cancer

43 locations incl. Anchorage

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06161025·Phase 2, Phase 3·Recruiting

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The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation.

for Paroxysmal Atrial Fibrillation

21 locations incl. Birmingham

Sponsor: Heart Rhythm Clinical and Research Solutions, LLC

Sex: All·Age: 18+

Code: NCT06324201·Recruiting

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CD33KO-HSPC Infusion Followed by CART-33 Infusion(s) for Refractory/Relapsed AML

for Leukemia, Myeloid, Acute

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05945849·Phase 1·Recruiting

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SNV1521 in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

5 locations incl. New Haven

Sponsor: Synnovation Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06220864·Phase 1·Recruiting

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NS-089/NCNP-02-201 in Boys With Duchenne Muscular Dystrophy (DMD)

for Duchenne Muscular Dystrophy

10 locations incl. Aurora

Sponsor: NS Pharma, Inc.

Sex: Male·Age: 4 - 14

Code: NCT05996003·Phase 2·Recruiting

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An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema

for Emphysema, Pulmonary

18 locations incl. Phoenix

Sponsor: Pulmonx Corporation

Sex: All·Age: 40 - 80

Code: NCT06035120·Recruiting

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Gram-Negative Bloodstream Infection Oral Antibiotic Therapy Trial

for Gram-negative Bacteremia

11 locations incl. San Francisco

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06080698·Recruiting

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A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

for COPD (Chronic Obstructive Pulmonary Disease)

234 locations incl. Athens

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06283966·Phase 3·Recruiting

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A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1)

for Myotonic Dystrophy Type 1 (DM1)

8 locations incl. San Carlos

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 64

Code: NCT06185764·Phase 1, Phase 2·Recruiting

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SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation

for Acute Myeloid Leukemia With FLT3/ITD Mutation

4 locations incl. Chapel Hill

Sponsor: Uma Borate

Sex: All·Age: 18+

Code: NCT06222580·Phase 1·Recruiting

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An Observational Study of Patients With Chronic Liver Disease

for Chronic Liver Disease

10 locations incl. Los Angeles

Sponsor: Target PharmaSolutions, Inc.

Sex: All·Age: 18+

Code: NCT05744713·Enrolling By Invitation

A Global Prospective Observational Registry of Patients With Pompe Disease

for Pompe Disease

15 locations incl. Little Rock

Sponsor: Amicus Therapeutics

Sex: All·Age: All ages

Code: NCT06121011·Recruiting

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RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

21 locations incl. Orange

Sponsor: Cabaletta Bio

Sex: All·Age: 18 - 65

Code: NCT06121297·Phase 1, Phase 2·Recruiting

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Study of Biodistribution, Metabolism, Excretion and Brain Uptake11C-M503

for Tauopathies

3 locations incl. New Haven

Sponsor: University of Pennsylvania

Sex: All·Age: 40 - 85·Accepts healthy volunteers

Code: NCT06303921·EARLY_Phase 1·Recruiting

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Real-time fMRI for Insular Cortex Brain State-triggered Experience Sampling

for Healthy

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT05855525·Recruiting

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Getting Out of the House: Using Behavioral Activation to Increase Community Participation

for Major Depressive Disorder

1 location in Philadelphia

Sponsor: Temple University

Sex: All·Age: 18+

Code: NCT06336616·Recruiting

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Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

for Differentiated Thyroid Cancer

5 locations incl. San Francisco

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 2 - 99

Code: NCT05783323·Phase 2·Recruiting

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An Acceptance-Based Healthy Lifestyle Intervention for Diverse Adolescents

for Overweight and Obesity

1 location in Philadelphia

Sponsor: Drexel University

Sex: Female·Age: 14 - 19·Accepts healthy volunteers

Code: NCT06147973·Recruiting

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Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia

for Primary Progressive Aphasia

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 50 - 90·Accepts healthy volunteers

Code: NCT05386394·Phase 2·Recruiting

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Tocilizumab in Lung Transplantation

for Lung Transplant

Drug: Tocilizumab

21 locations incl. Phoenix

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12 - 75

Code: NCT06033196·Phase 2·Recruiting

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A Natural History Study in Participants With Congenital Myasthenic Syndromes (CMS) Due to Mutations in DOK7, MUSK, AGRN, or LRP4

for Congenital Myasthenic Syndrome

6 locations incl. Sacramento

Sponsor: argenx

Sex: All·Age: 2+

Code: NCT06078553·Recruiting

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A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

for Advanced Solid Tumors With KRAS G12C Mutations

15 locations incl. La Jolla

Sponsor: Frontier Medicines Corporation

Sex: All·Age: 18+

Code: NCT06244771·Phase 1, Phase 2·Recruiting

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Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis (IPF)

12 locations incl. Birmingham

Sponsor: InSilico Medicine Hong Kong Limited

Sex: All·Age: 40+

Code: NCT05975983·Phase 2·Recruiting

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A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

for Antineutrophil Cytoplasmic Antibody-associated Vasculitis

60 locations incl. Anchorage

Sponsor: Amgen

Sex: All·Age: 18 - 100

Code: NCT06072482·Phase 4·Recruiting

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Hypertension and Arrhythmias in CLL Patients Treated With BTK Inhibitors

for Chronic Lymphocytic Leukemia

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 22+

Code: NCT06211413·Enrolling By Invitation

An Observational Study Comparing Delandistrogene Moxeparvovec (ELEVIDYS) With Standard of Care in Participants With Duchenne Muscular Dystrophy

for Duchenne Muscular Dystrophy

25 locations incl. Little Rock

Sponsor: Sarepta Therapeutics, Inc.

Sex: Male·Age: 4+

Code: NCT06270719·Enrolling By Invitation

Nerve Transfer to Improve Function in High Level Tetraplegia

for Cervical Spinal Cord Injury

9 locations incl. Stanford

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 80

Code: NCT06288763·Recruiting

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Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

for Muscle Invasive Bladder Urothelial Carcinoma

491 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05987241·Phase 2, Phase 3·Recruiting

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A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

for Esophageal Cancer

10 locations incl. Boston

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06123338·Phase 2·Recruiting

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Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)

for Idiopathic Pulmonary Fibrosis

19 locations incl. La Mesa

Sponsor: Cumberland Pharmaceuticals

Sex: All·Age: 40+

Code: NCT05571059·Phase 2·Recruiting

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TmPSMA-02 in mCRPC

for Metastatic Castrate-Resistant Prostate Cancer (mCRPC)

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Male·Age: 18+

Code: NCT06046040·Phase 1·Recruiting

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Dosing of LT4 in Older Individuals

for Hypothyroidism

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 65+

Code: NCT06073665·Phase 4·Recruiting

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Enriched Holistic Care to Eradicate Disparities in Maternal Morbidity

for Morbidity

2 locations incl. Phialdelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 16 - 55·Accepts healthy volunteers

Code: NCT06245057·Recruiting

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Feasibility of Semaglutide in Advanced Lung Disease

for Obesity

Drug: Semaglutide

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 80

Code: NCT05746039·Phase 1, Phase 2·Recruiting

Apply to this trial